Biophysical Society 60th Annual Meeting

Platform Molecular, Cellular, and Experimental Neuroscience: Reception, Plasticity,

1817-Plat 5:15 pm EVOLUTION UNDER DRUG PRESSURE REMODELS THE FOLDING FREE- ENERGY LANDSCAPE OF HIV-1 PROTEASE.  Julien Roche 1818-Plat 5:30 pm FOLDING MECHANISM OF A METASTABLE SERPIN AT ATOMIC RESOLU- TION.  Fang Wang, Haiping Ke, Silvio a Beccara, Anne Gershenson, Pietro Faccioli, Patrick Wintrode 1819-Plat 5:45 pm NMR-INFORMED MOLECULAR MODELING UNCOVERS THE CONFORMA- TIONAL LANDSCAPE OF CHAPERONE BINDING WITH UNFOLDED SUB- STRATE.  Logan S. Ahlstrom , Loïc Salmon, Scott Horowitz, Alex Dickson, Charles L. Brooks III, James C.A. Bardwell Platform Membrane Physical Chemistry III 4:00 pm - 6:00 pm, Room 515A Co-Chairs Padmini Rangamani, University of California, San Diego Joseph Zasadzinski, University of Minnesota 1820-Plat 4:00 pm ELASTIC DEFORMATION AND COLLECTIVE DYNAMICS IN LIPID MEM- BRANES: A SOLID-STATE 2 H NMR RELAXATION STUDY.  Soohyun K. Lee , Trivikram R. Molugu, K.J. Mallikarjunaiah, Michael F. Brown 1821-Plat 4:15 pm CHOLESTEROL EFFECT ON THE ELASTIC PROPERTIES OF UNSATURATED LIPID BILAYERS.  Pavel Bashkirov , Ksenia Chekashkina, Ariana Velasco del Olmo, Piotr Kuzmin, Anna Shnyrova, Vadim Frolov 1822-Plat 4:30 pm QUANTITATIVE RELATIONSHIP BETWEEN MONOLAYER DOMAIN STRUC- TURE AND INTERFACIAL SHEAR RHEOLOGY.  Joseph A. Zasadzinski 1823-Plat 4:45 pm TWO-POINT MICRORHEOLOGY OF PHASE SEPARATED DOMAINS IN LIPID BILAYERS.  Tristan Hormel , Matthew A. Reyer, Raghuveer Parthasarathy 1824-Plat 5:00 pm IN SILICO MEASUREMENT OF THE MECHANICAL PROPERTIES OF REALIS- TIC BACTERIAL INNER AND OUTER MEMBRANES.  Hyea Hwang , James C. Gumbart 1825-Plat 5:15 pm CAN WE TRUST HYDRODYNAMIC MODELS TO DETERMINE THE BILAYER VISCOSITY EXPERIENCED BY TRANSMEMBRANE PROTEINS?  Vladimir Adrien , Ksenia Astafyeva, Marina Kuimova, Wladimir Urbach, Nicolas Taulier 1826-Plat 5:30 pm COMBINING FLUORESCENCE MICROSCOPY ON FREESTANDING LIPID BI- LAYERS WITH ELECTRICAL MEASUREMENTS.  Corianne C. van den Akker , Steven G. Boxer 1827-Plat 5:45 pm IRREVERSIBLE THERMODYNAMICS OF LIPID VESICLES UNDER OSMOTIC STRESS. Morgan Chabanon , James Ho, Atul N. Parikh, Padmini Rangamani

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and New Approaches 4:00 pm - 6:00 pm, Room 515B

Co-Chairs Laura Marchetti, Center for Nanotechnology Innovation, Italy Katalin Torok, St. George’s, University of London, United Kingdom 1828-Plat 4:00 pm SINGLE MOLECULE IMAGING AND TRACKING OF NEUROTROPHINS AND THEIR RECEPTORS IN LIVING NEURONAL CELLS.  Laura Marchetti , Teresa De Nadai, Rosy Amodeo, Carmine Di Rienzo, Fulvio Bonsignore, Francesco Gobbo, Fabio Beltram, Stefano Luin, Antonino Cattaneo 1829-Plat 4:15 pm SINGLE MOLECULAR OBSERVATION OF DIFFUSIVE DYNAMICS OF NMDA RECEPTORS IN LIVE NEURONS USING SUPER-RESOLUTION IMAGING AND TRACKING.  Sang Hak Lee , En Cai, Pinghua Ge, Kai Wen Teng, Okunola Jeyifous, Sung Soo Jang, Hee-Jung Chung, William Green, Paul R. Selvin 1830-Plat 4:30 pm STOCHASTIC SINGLE-MOLECULE DYNAMICS OF SYNAPTIC RECEPTOR DOMAINS.  Yiwei Li , Osman Kahraman, Christoph Haselwandter 1831-Plat 4:45 pm PARADOXICAL SIGNALING REGULATES STRUCTURAL PLASTICITY IN DEN- DRITIC SPINES.  Padmini Rangamani , Michael Levy, Shahid Khan, George Oster 1832-Plat 5:00 pm NANO-MECHANICAL PROBING OF SYNAPTIC ACTIVITY AT DENDRITIC SPINES.  John A. Jones Molina , Nicola Mandriota, Duckhoe Kim, Ju Yang, Rafael Yuste, Ozgur Sahin 1833-Plat 5:15 pm DEVELOPMENT OF FAST-RESPONSE GCAMP6 CALCIUM SENSORS FOR MONITORING NEURONAL ACTION POTENTIAL.  Nordine Helassa, Borbala Podor, Alan Fine, Katalin Torok 1834-Plat 5:30 pm OPTOMEA: A PLATFORM FOR ANALYZING SIGNALING EFFICIENCY OF NEURONAL CIRCUITS USING MULTI-LOCATION EXTRACELLULAR ELECTRO- PHYSIOLOGY, OPTICAL IMAGING AND OPTOGENETICS.  Kimberly Sam, Minqi Wang, Yuan-Zhi Liu, Paritosh Pande, Stephen A. Boppart, Parijat 5:45 pm LIGHT SHEET MICROSCOPY FOR FUNCTIONAL IMAGING OF BRAIN ACTIV- ITY EVOKED BY NATURAL SENSORY STIMULI.  Andrey Andreev , Thai Truong, Scott E. Fraser Platform Optical Spectroscopy: CD, UV-VIS, Vibrational, Fluorescence 4:00 pm - 6:00 pm, Room 501ABC Co-Chairs Sengupta 1835-Plat

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Mark Bowen, Stony Brook University David Thomas, University of Minnesota 1836-Plat 4:00 pm

FLUORESCENT PROTEIN FRET AS A PROBE OF PROTEIN CONFORMATION IN VIVO AND IN VITRO.  Laura Dougherty, Zhuojun Guo, Fang Wu, Mark E. Bowen

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