Biophysical Society 60th Annual Meeting

3072-Pos Board B449 SEGREGATION OF MOBILE NUCLEAR PROTEINS AWAY FROM CHROMA- TIN WHEN THE NUCLEUS IS CONSTRICTED. Charlotte R. Pfeifer , Jerome Irianto, Dennis E. Discher 3073-Pos Board B450 A CHEMO-MECHANICAL MODEL FOR EXTRACELLULAR MATRIX AND NU- CLEAR RIGIDITY REGULATED SIZE OF FOCAL ADHESION PLAQUES. Xuan Cao , Yuan Lin, Tristian P. Driscoll, Janusz Franco-Barraza, Edna Cukierman, Robert L. Mauck, Vivek Shenoy 3074-Pos Board B451 SPINDLE MICRO-FLUCTUATIONS OF LENGTH REVEAL ITS DYNAMICS OVER CELL DIVISION. Benjamin Mercat , Xavier Pinson, Jonathan Fouchard, Hadrien Mary, Sylvain Pastezeur, Zahraa Alayan, Yannick Gachet, Sylvie Tournier, Hélène Bouvrais, Jacques Pécréaux 3075-Pos Board B452 CPOW TRAVEL AWARDEE ACTOMYOSIN NETWORK CONTRACTILITY TRIGGERS A STOCHASTIC TRANSFORMATION INTO HIGHLY MOTILE AMOEBOID CELLS. Verena Ruprecht , Stefan Wieser, Andrew Callan-Jones, Michael Smutny, Hitoshi Morita, Keisuke Sako, Vanessa Barone, Monika Ritsch-Marte, Michael Sixt, Raphael Voituriez, Carl-Philipp Heisenberg 3076-Pos Board B453 CYTOSKELETAL AND ADHESION DYNAMICS ARE COUPLED TO MATRIX DEFORMATION IN 3D CELL MIGRATION. Leanna M. Owen , Arjun S. Adhikari, Mohak Patel, Natascha Leijnse, Min Cheol Kim, Christian Franck, Alexander R. Dunn 3077-Pos Board B454 HOMEOSTASIS OF PLASMA MEMBRANE TENSION THROUGH SURFACE AREA REGULATION IN EPITHELIAL CELLS. Andreas Janshoff , Bastian Brueckner, Stefan Nehls 3078-Pos Board B455 CELL MOTILITY AND GROWTH FACTORS ACCORDING TO DIFFERENTIALLY VARIATIONAL SURFACES. David V. Svintradze 3079-Pos Board B456 CELLULAR ADHESION: EVALUATING THE EFFECT OF RECEPTOR-LIGAND CHEMISTRIES, DISTRIBUTION OF RECEPTORS, AND SPREAD VERSUS SPHERICAL CELL GEOMETRY. Aravind R. Rammohan , MathewMckenzie, Ravi Radhakrishnan, Natesan Ramakrishnan 3080-Pos Board B457 CELL FORMATION AND COMPETITION IN THREE DIMENSIONS. Anqi Huang, Jianmin Yin, Weimiao Yu, Timothy E. Saunders 3081-Pos Board B458 MECHANICAL PROPERTIES OF DIFFERENTIATING STEM CELLS ON PEPTIDE NANOFIBERS. Ahmet E. Topal , Ayse B. Tekinay, Mustafa O. Guler, Aykutlu Dana 3082-Pos Board B459 INTERNATIONAL TRAVEL AWARDEE COHERENT MOTION OF MONOLAYER SHEETS UNDER ACTIVE AND PAS- SIVE CONFINEMENT: FROM BUILD-UP TO CONSEQUENCE. SS Soumya , Dibyendu Das, Shamik Sen, Mandar M. Inamdar 3083-Pos Board B460 MECHANOBIOLOGICAL INDUCTION OF LONG-RANGE CONTRACTILITY AND SIZE SCALING IN CELL ASSEMBLIES. Kinjal Dasbiswas , Samuel Safran 3084-Pos Board B461 CORTICAL FLOW-DRIVEN SHAPES OF NON-ADHERENT CELLS. Andrew Callan-Jones , Verena Ruprecht, Stefan Wieser, Carl-Philipp Heisenberg, Raphaël Voituriez 3085-Pos Board B462 AN ACTIVE CONTRACTION MODEL OF VALVULAR INTERSTITIAL CELLS.  Yusuke Sakamoto, Michael S. Sacks

3086-Pos Board B463 MULTI-CELLULAR MECHANICAL REGULATION OF ENDOTHELIAL PERME- ABILITY. Corey Hardin , Ramaswamy Krishnan, Emanuela Del Gado Membrane Pumps, Transporters, and Exchangers II (Boards B464 - B490) 3087-Pos Board B464 THE MECHANICAL INSIGHTS INTO PROTON/ELECTRON TRANSFER IN CYTOCHROME C OXIDASE REVEALED BY DIRECT MODELING OF VOLT- AGE CHANGES IN RESPONSE TO CHARGE SEPARATION.  Ilsoo Kim , Arieh Warshel 3088-Pos Board B465 WHAT KEEPS TOLC CLOSED? INSIGHTS FROMMOLECULAR DYNAMICS SIMULATIONS. Fabio Grassi , Vassiliy N. Bavro, Ulrich Kleinekathöfer 3089-Pos Board B466 SPONTANEOUS INWARD OPENING OF THE DOPAMINE TRANSPORTER IS TRIGGERED BY PIP2-REGULATED DYNAMICS OF THE N-TERMI- NUS. George Khelashvili , Nathaniel Stanley, Michelle Sahai, Jaime Medina, Michael V. LeVine, Lei Shi, Gianni De Fabritiis, Harel Weinstein 3090-Pos Board B467 COMPUTATIONAL INVESTIGATION OF THE TRANSPORT MECHANISM OF NEUROTRANSMITTER SODIUM SYMPORTERS USING A PHYSIOLOGICAL ION GRADIENT. Emily M. Benner , Jeffry D. Madura 3091-Pos Board B468 TOWARDS IDENTIFYING BIOLOGICALLY RELEVANT INTERMEDIATE CON- FORMATIONAL STATES IN DOPAMINE TRANSPORTER. Ara M. Abramyan , Nicholas Taro, Sebastian Stolzenberg, Lei Shi 3092-Pos Board B469 KEEPING SECONDARY TRANSPORTERS UNDER CONTROL: LESSONS FROM A NA + /CA 2+ EXCHANGER. Fabrizio Marinelli , José Faraldo-Gómez 3093-Pos Board B470 CID TRAVEL AWARDEE COMBINED QM/MM DYNAMICS SIMULATIONS OF PROTON TRANSFER IN E. COLI CLC CHLORIDE/PROTON ANTIPORTER. Christina Garza 3094-Pos Board B471 COMPUTATIONAL STUDIES OF ELEVATOR-LIKE MOVEMENTS IN SECOND- ARY TRANSPORT. Cristina Fenollar-Ferrer, Claudio Anselmi, Ariela Vergara Jaque, Hossein Ali Karimi-Verzaneh, Horacio Poblete-Vilches, Christopher Mulligan, Ian C. Forster, Joseph A. Mindell, José D. Faraldo-Gómez, Lucy Board B472 DISSECTING FUNCTIONAL CORRELATES OF A DOUBLE MUTATION ENHANCING GLTPH TRANSPORT EFFICIENCY USING ALCHEMICAL FREE ENERGY CALCULATIONS. Michel A. Cuendet , Harel Weinstein 3096-Pos Board B473 HIGH-RESOLUTION STRUCTURES AND MOLECULAR DYNAMICS SIMU- LATIONS OF THERMUS THERMOPHILUS NAPA REVEAL A LARGE-SCALE CONFORMATIONAL CHANGE FOR ION TRANSLOCATION. David L. Dotson , Mathieu Coincon, Povilas Uzdavinys, Emmanuel Nji, Iven Winkelmann, Saba Abdul-Hussein, Alexander D. Cameron, David Drew, Oliver Beckstein 3097-Pos Board B474 STRUCTURAL CHARACTERIZATION OF SUBSTRATE TRANSPORT SELEC- TIVITY OF THE SLC13 FAMILY OF NA + /DICARBOXYLATE COTRANSPORT- ERS. Claire Colas , Ana M. Pajor, Avner Schlessinger 3098-Pos Board B475 A MOLECULAR DYNAMICS BASED MODEL OF THE OUTWARD-FACING STATE AND TRANSPORT MECHANISM OF THE HUMAN NACT HOMOLOG VCINDY. Noah Trebesch , Joshua V. Vermaas, Emad Tajkhorshid R. Forrest 3095-Pos

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