Biophysical Society 60th Annual Meeting

587-Pos Board B367 CSFV P7 VIROPORIN ION CHANNEL ACTIVITY IN LIPID BILAYERS MIMICK- ING THE ER MEMBRANE. Vicente M. Aguilella , Eneko Largo, Carmina Verdiá-Báguena, José L. Nieva, Antonio Alcaraz 588-Pos Board B368 ELECTRO-OSMOTIC DRIVEN KINETICS OF CYCLODEXTRIN THROUGH THE CYMA CHANNEL. Satya Prathyusha Bhamidimarri , Jigneshkumar Dahyabhai Prajapati, Bert van den Berg, Ulrich Kleinekathoefer, Mathias Winterhalter 589-Pos Board B369 INTERNAL ELECTRIC FIELD OF GRAM- UNSPECIFIC PORINS DIRECTS THE CHOREOGRAPHY OF ANTIBIOTIC TRANSLOCATION. Mariano A. Scorciap- ino , Tommaso D’Agostino, Silvia Acosta-Gutierrez, Igor Bodrenko, Matteo Ceccarelli 590-Pos Board B370 INTERNATIONAL TRAVEL AWARDEE WATER-BASED SCREENING OF ANTIBIOTICS PERMEABILITY. Silvia Acosta- Gutierrez , Andrea Mariano Scorciapino, Igor Bodrenko, Matteo Ceccarelli 591-Pos Board B371 GSMTX4 MUTAGENESIS REVEALS DYNAMIC MEMBRANE BINDING PROP- ERTIES THAT CONFER INHIBITION OF PIEZO1. Radhakrishnan Gnanasam- bandam , Chiranjib Ghatak, Anthony Yasmann, Frederick Sachs, Alexey S. Ladokhin, Sergei I. Sukharev, Thomas M. Suchyna 592-Pos Board B372 INTERNATIONAL TRAVEL AWARDEE THE N-TERMINAL HELIX ACTS AS A DYNAMIC MEMBRANE COUPLER IN THE GATING CYCLE OF THE MECHANOSENSITIVE CHANNEL MSCL. Navid Bavi , Charles D. Cox, Paul R. Rohde, Adam P. Hill, Ben Corry, Boris Board B373 ASSESSING CLC-2 CHLORIDE CHANNEL VOLTAGE GATING BY PORE OCCU- PATION WITH ACETATE.  José J. De Jesús-Pérez , Jorge Arreola 594-Pos Board B374 SPONTANEOUS OPENINGS OF CFTR ARE COUPLED TO DIMER FORMA- TION OF ITS NUCLEOTIDE BINDING DOMAINS. Csaba Mihályi , László Board B375 THE PROSTACYCLIN ANALOG TREPROSTINIL INHIBITS ANO1-ENCODED CA 2+ -ACTIVATED CL- CHANNELS AND MOUSE PULMONARY ARTERIAL TONE THROUGH STIMULATION OF CAMP-DEPENDENT SIGNALING PATH- WAY. Fiona Cunningham, John Lilly, Normand Leblanc 596-Pos Board B376 FUNCTIONAL DIVERSITY WITHIN THE FNT SUPERFAMILY OF ANION CHANNELS: PHYLOGENETICS & MOLECULAR DYNAMICS STUDIES. Mishtu Mukherjee , Manu Vajpai, Ramasubbbu Sankararamakrishnan 597-Pos Board B377 BASIS OF NEGATIVE COOPERATIVITY IN TWO-SIDED MONOBODY BLOCK OF FLUC. Daniel L. Turman , Jake Nathanson, Randy Stockbridge, Chris Miller 598-Pos Board B378 A BACTERIAL HOMOLOG OF CHLORIDE INTRACELLULAR CHANNEL (CLIC) PROTEIN FAMILY, STRINGENT STARVATION PROTEIN A (SSPA), FORMS A NON-SELECTIVE ION CHANNEL. Harpreet Singh , Devasena Ponnalagu, Sowmya Sukur, Harkewal Singh, Yan Ning Zhou, Ding J. Jin, Shubha Gururaja Rao 599-Pos Board B379 NEAR-IR RESONANCE RAMAN CHARACTERIZATION OF AN ANION CHAN- NELRHODOPSIN FROM GUILLARDIA THETA. Adrian Yi , Natalia Mamaeva, Hai Li, John L. Spudich, Kenneth J. Rothschild Martinac 593-Pos Csanády 595-Pos

574-Pos Board B354 MAPPING RECEPTOR SITES FOR SODIUM CHANNEL BLOCKING INSECTI- CIDES DCJW AND METAFLUMIZONE IN AN INSECT SODIUM CHANNEL.  Yuzhe Du, Yongqiang Zhang, Dingxin Jiang, Caitlyn Behnke, Yoshiko Nomura, Ke Dong, Boris S. Zhorov 575-Pos Board B355 MECHANISM OF SLOW INACTIVATION IN PROKARYOTIC VOLTAGE-GATED SODIUM CHANNEL. Soumili Chatterjee 576-Pos Board B356 DIFFERENTIAL ACTION OF PYRETHROIDS ON HONEY BEE AND BUMBLE BEE VOLTAGE-GATED SODIUM CHANNELS. Claude Collet , Aklesso Kadala, Bernard Vaissière, Matthieu Rousset, Thierry Cens, Yves Le Conte, Mohamed Chahine, Jean-Baptiste Thibaud, Pierre Charnet 577-Pos Board B357 IDENTIFICATION OF NOVEL PORE INTERACTIONS FOR SELECTIVE NAV1.8 INHIBITORS. Matthew D. Fuller , Sonia Santos, Mark L. Chapman 578-Pos Board B358 CHARACTERIZATION OF NAV1.8 ON A HIGHLY PARALLEL AUTOMATED PATCH CLAMP SYSTEM. Markus Rapedius , Andrea Bruggemann, Tom Goetze, Claudia Haarmann, Ilka Rinke, Atsushi Ohtsuki, Takayuki Oka, Marius Vogel, Timo Stengel, Johannes Stiehler, Michael George, Nils Fertig 579-Pos Board B359 THE EFFECTS OF AMIODARONE AND N-DESETHYLAMIODARONE ON CAR- DIAC VOLTAGE-GATED SODIUM CHANNELS. Mohammad-Reza Ghovanloo , Peter C. Ruben 580-Pos Board B360 HIGH AFFINITY NAV CHANNEL BINDER WITH SPECIFIC CONJUGATION SITE DERIVED FROM SCORPION TOXIN WITH ATTENUATED TOXICITY. Tomoya Kubota , Bobo Dang, Joao L. Carvalho-de-Souza, Stephen B.H. Kent, Ana M. Correa, Francisco Bezanilla 581-Pos Board B361 PROBING VOLTAGE-DEPENDENT STRUCTURAL CHANGES OF THE VSD IN MAMMALIAN NAV WITH LRET. Tomoya Kubota , Thomas Durek, Rocio K. Finol-Urdaneta, David J. Craik, Robert J. French, Francisco Bezanilla, Ana M. Correa Other Channels (Boards B362 - B390) 582-Pos Board B362 STRUCTURAL DETERMINANTS FOR SELECTIVITY OF THE POSITIVE KCA CHANNEL GATING MODULATOR, SKA-121. Brandon M. Brown , Heesung Shim, Vladimir Yarov-Yarovoy, Heike Wulff 583-Pos Board B363 BK-CA 2+ CHANNEL COUPLING IN THE MOUSE CIRCADIAN CLOCK. Joshua P. Whitt, Andrea L. Meredith 584-Pos Board B364 LOSS-OF-FUNCTIONAL KIR6.1 KATP CHANNEL MUTATIONS INDUCE CELL APOPTOSIS THROUGH ROS PRODUCTION AND MITOCHONDRIAL DYS- FUNCTION. Bi-Hua Tan , Shengyi Xie, Tianyu Sun, Sinisa Dovat, Blaise Z. Peterson, Chunhua Song 585-Pos Board B365 HUMAN ERYTHROCYTE MECHANO-ACTIVATED K + CHANNEL A (HEM- KCA): EFFECT OF APPLIED PRESSURE ON OPEN PROBABILITY, A KINETIC STUDY. Alejandro Mata, Jesus G. Romero 586-Pos Board B366 CATSPER HAS A CALCIUM-PERMEABLE VOLTAGE SENSOR DOMAIN.  Hiroki Arima , Hidekazu Tsutsui, Kohei Takeshita, Atsushi Nakagawa, Ayako Sakamoto, Manabu Yoshida, Yasushi Okamura

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