Biophysical Society 60th Annual Meeting

721-Pos Board B501  NON-INVASIVE FLUORESCENCE LIFETIME IMAGING(FLIM) OF STEM CELL SIGNATURE METABOLIC STATES. Ning Ma , Michelle Digman, Peter

708-Pos Board B488 MECHANISMS OF BACTERIAL ABC IMPORTERS: LESSONS FROM STRUC- TURAL AND FUNCTIONAL STUDIES OF THE RIBOSE TRANSPORTER.  Satchal K. Erramilli , Michael J. Simon, Matthew C. Clifton, Cynthia V. Stauffacher 709-Pos Board B489 REFINEMENT OF A RECENT CFTR HOMOLOGY MODEL GUIDED BY PORE FORMATION. Gorman Stock, Nael McCarty, James C. Gumbart 710-Pos Board B490 IN SILICO CHARACTERIZATION OF P-GLYCOPROTEIN SUBSTRATE EN- TRANCE PATHWAYS. Laura Domicevica, Teresa Paramo, Philip C. Biggin Cellular Signaling and Metabolic Networks (Boards B491 - B517) 711-Pos Board B491 3D SIMULATIONS OF MORPHOGEN TRANSPORT IN AN EARLY FISH EM- BRYO.  Ines Reinartz , Claude Sinner, Eliana Stanganello, Benjamin Mattes, Steffen Scholpp, Alexander Schug 712-Pos Board B492 TRANSPLANTATION OF MESENCHYMAL STEM CELLS ENHANCES ANGIO- GENESIS AFTER ISCHEMIC LIMB INJURY IN MICE. Hua Zhu , Nanzi Xie, Timothy Adesanya, Ahmet Kilic, Tao Tan, Xiaoyun Xie 713-Pos Board B493 QUANTIFICATION OF THE NUTRIENT DEPENDENCE OF FACTORS CON- TROLLING START IN BUDDING YEAST BY 2-PHOTON SCANNING NUMBER AND BRIGHTNESS. Savanna B. Dorsey , Sylvain Tollis, Jing Cheng, Linnea Olofsson, Mike Tyers, Catherine A. Royer 714-Pos Board B494 TOWARDS PREDICTIVE MODELING OF INFORMATION PROCESSING IN MICROBIAL ECOSYSTEMS WITH QUORUM SENSING INTERACTIONS. Tahir Yusufaly , James Boedicker 715-Pos Board B495 BCL-2 OR BCL-XL OVEREXPRESSION STIMULATES BOTH OXIDATIVE AND FERMENTATIVE COMPONENTS OF CARBOHYDRATE METABOLISM. Bushra Mahmood, Jessica Wilson, Miriam Ahmad, Patricia Olino, Hooi Chong, Diana Lopez, Justin King, Rhaul Llanos, Laurent M. Dejean 716-Pos Board B496 KINETIC PROPERTIES AND REDOX REGULATION OF RECOMBINANT CALCIUM-INDEPENDENT PHOSPHOLIPASE A2γ RECONSTITUTED IN LIPO- SOMES. Martin Jaburek , Petr Jezek 717-Pos Board B497 UNDERSTANDING DOPAMINE RECEPTOR MEDIATED REGULATION OF INSULIN SECRETION BY TWO-COLOR SPATIAL INTENSITY DISTRIBUTION ANALYSIS. Daniel Foust , Brittany Caldwell, Antoine Godin, Alessandro Ustione, Paul Wiseman, David Piston 718-Pos Board B498 SPATIO-TEMPORAL DYNAMICS OF QUORUM SENSING SIGNALS. Pavan Silva , James Boedicker 719-Pos Board B499 TUDCA RESCUES β-CELL METABOLIC OSCILLATIONS FROM ER STRESS, REVEALED BY NAD(P)H-FLIM AND FRET. Chetan Poudel , Brian A. Schmidt, Quincy E. Harenda, Feyza Engin, Kevin W. Eliceiri, Matthew J. Merrins 720-Pos Board B500 HIGH-ORDER INTERACTIONS BETWEEN SPECIES STRONGLY INFLUENCE THE ACTIVITY OF MICROBIAL COMMUNITIES. Xiaokan Guo , James Boedicker

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Donovan 722-Pos

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Board B502 TEMPORAL MODULATION OF A GPCR PATHWAY ELUCIDATES BAND-PASS PROCESSING FOR THE DOWNSTREAM SIGNALING AND TRANSCRIPTION FACTOR ACTIVATION. Madhuresh Sumit , Richard R. Neubig, Shuichi Takayama, Jennifer J. Linderman 723-Pos Board B503 LIMITATIONS OF THE USE OF THE PI4-KINASE INHIBITOR WORTMAN- NIN IN EXPERIMENTS EMPLOYING FLUORESCENT PHOSPHOINOSITIDE PROBES. Christian R. Halaszovich , Dominik Oliver 724-Pos Board B504 SYSTEMS BIOLOGY APPROACH REVEALS THE IMPORTANCE OF SHC1- GRB2 INTERACTIONS IN EGFR PHOSPHORYLATION KINETICS. Emanuel Salazar-Cavazos , Luis G. Contreras-Vidal, Bridget S. Wilson, William S. Hlavacek, Diane S. Lidke 725-Pos Board B505 THE ACTIN CYTOSKELETON MEDIATES HYPEROXIA RESPONSE OF PATIENT-DERIVED PRIMARY ENDOTHELIAL PROGENITOR CELLS THROUGH THYMOSIN BETA-4 AND HYPOXIA-INDUCIBLE FACTOR SIGNALING. Jenni- fer Larmore, Claudine Black, Gregory Seedorf, Christopher Baker, Douglas Shepherd 726-Pos Board B506 LOCAL PHEROMONE RELEASE FROM DYNAMIC POLARITY SITES UNDER- LIES CELL-CELL PAIRING DURING YEAST MATING. Laura Merlini, Felipe O. Bendezu, Bita Khalili, Daniel Hurwitz, Vincent Vincenzetti, Dimitrios Vavylonis , Sophie G. Martin 727-Pos Board B507 FROZEN PROTEIN CONCENTRATIONS AND SURVIVAL OF INFORMATION DURING SHIFTS IN BACTERIAL GROWTH.  Joe Christian J. Ray , Arnab Bandyopadhyay 728-Pos Board B508 AGING OF INDIVIDUAL CELLS OVER TENS OF GENERATIONS. Charles Wright , Srividya Iyer-Biswas 729-Pos Board B509 QUANTITATIVE CHARACTERIZATION OF INTRACELLULAR COMPARTMENT- SPECIFIC REACTIVE OXYGEN SPECIES (ROS) DYNAMICS IN A HEART FAILURE MODEL OF ARRHYTHMIC SUDDEN CARDIAC DEATH (SCD). Swati Dey , Deeptankar DeMazumder, Brian O’Rourke 730-Pos Board B510 2-HYDROXYGLUTARATE PRODUCTION BY MUTANT ISOCITRATE DEHYDRO- GENASE IS INDEPENDENT OF SUBSTRATE CHANNELING BUT SENSITIVE TO COMPARTMENT-SPECIFIC METABOLITE LEVELS.  Joseph P. Dexter , Patrick S. Ward, Tathagata Dasgupta, Aaron M. Hosios, Jeremy Gunawardena, Matthew G. Vander Heiden 731-Pos Board B511 MULTISCALE GEONAVIGATIONAL APPROACH TO UNDERSTAND ORGAN BIOSYSTEMS AND THEIR CELLULAR INHABITANTS IN HEALTH AND DIS- EASE. Melissa Knothe Tate, André F. Pereira , Dirk Zeidler, Daniel Hageman, Ulf R. Knothe 732-Pos Board B512 REAL-TIME 3D IMAGING AT THE SINGLE MOLECULE LEVEL OF SIGNAL TRANSDUCTION IN SACCHAROMYCES CEREVISIÆ RESPONDING TO ENVI- RONMENTAL CHANGES. Erik G. Hedlund , Sviatlana Shashkova, Adam J. M. Wollman, Stefan Hohmann, Mark C. Leake

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