Biophysical Society 60th Annual Meeting

Protein Structure and Conformation II (Boards B1 - B18) 1024-Pos Board B1 REVEALING ACTIVATION MECHANISM OF ALK2 KINASE MUTATIONS IN FIBRODYSPLASIA OSSIFICANS PROGRESSIVA (FOP). Abdelaziz Alsamarah, Jijun Hao, Yun Luo 1025-Pos Board B2 A COMPARATIVE STUDY OF GAMMA SUBUNITS OF A.THALIANA AND O.SATIVA. Bihter Avsar , Ines Karmous, Ersoy Colak, Zehra Sayers 1026-Pos Board B3 STRUCTURAL AND FUNCTIONAL BASIS OF ALTERNATIVE ESCRT-0 PROTEIN COMPLEXES. Shuyan Xiao, Xiaolin Zhao, Wen Xiong, Mary K. Brannon, Kristen Fread, Jeffrey Ellena, John Bushweller, Carla V. Finkielstein, Geoffrey Armstrong, Daniel G. Capelluto 1027-Pos Board B4 INSIGHTS INTO THE AUTOINHIBITION MECHANISM OF THE TIAM1 GUANINE NUCLEOTIDE EXCHANGE FACTOR. Zhen Xu , Lokesh Gakhar, Elizabeth Boehm, Todd Washington, Maria Spies, Ernesto J. Fuentes 1028-Pos Board B5 STRUCTURES OF HUMAN PHOSPHOFRUCTOKINASE-1 AND ATOMIC BASIS OF CANCER-ASSOCIATED MUTATIONS. Bradley Webb , Farhad Forouhar, Fu-En Szu, Jayaraman Seetharaman, Liang Tong, Diane Barber 1029-Pos Board B6 COMPARISON OF THE ENERGETICS OF HISTONE PEPTIDE BINDING AMONG HISTONE READERS. Suvobrata Chakravarty , Francisca Essel, Tao Lin 1030-Pos Board B7 SIMULATING MTOR HYPERACTIVATING MUTATIONS TO UNDERSTAND FUNCTIONALLY SIGNIFICANT STRUCTURAL REARRANGEMENTS. Steven Albanese , Jianing Xu, James Hsieh, John D. Chodera 1031-Pos Board B8 PROMISCUITY AND POLYREACTIVITY OF ANTIBODIES AND THEIR BINDING MODES DURING B-CELL DIFFERENTIATION. Franca Fraternali , Julie Laffy, Deborah Dunn-Walters 1032-Pos Board B9 IMPLICATION OF NATURAL POLYMORPHISM IN HINGE REGION OF HIV-1 PROTEASE ON PROTEIN CONFORMATIONS, LOCAL STRUCTURES AND BACKBONE DYNAMICS. Zhanglong Liu , Xi Huang, Lingna Hu, Linh Pham, Katye Poole, Yan Tang, Brian P. Mahon, Wenxing Tang, Kunhua Li, Nathan E. Goldfarb, Ben M. Dunn, Robert McKenna, Gail E. Fanucci 1033-Pos Board B10 CATCHING EXCITED STATES IN THE ACT: FUNCTIONAL UNFOLDING IN E. COLI ADENYLATE KINASE.  Jeremy A. Anderson , Ananya Majumdar, Vincent J. Hilser 1034-Pos Board B11 STRUCTURAL INVESTIGATION INTO CALMODULIN’S ROLE IN ACTIVAT- ING BORDETELLA PERTUSSIS ADENYLYL CYCLASE TOXIN CYAA. Tzvia I. Springer , Christian Johns, Natosha L. Finley 1035-Pos Board B12 TROPONIN STRUCTURE AND EFFECTS OF PHOSPHORYLATION AND MUTATIONS STUDIED BY MOLECULAR DYNAMICS SIMULATIONS.  Juan Eiros Zamora , Alice Sheehan, Maria Papadaki, Andrew E. Messer, Steven B. Marston, Ian R. Gould 1036-Pos Board B13 CALCIUM ION SIGNALING CASCADES THROUGH THE MECHANISM OF MODULATED MUTUALLY INDUCED CONFORMATION IN DOWNSTREAM PROTEINS.  Jacob Ezerski

1037-Pos Board B14 CONFORMATIONAL EFFECTS OF THE C-TERMINAL TAIL ON THE HUMAN NEURONAL CALCIUM SENSOR-1 PROTEIN: AN ATOMISTIC SIMULATION STUDY. Yuzhen Zhu , Qingwen Zhang 1038-Pos Board B15 NMR STRUCTURAL STUDIES OF THE C-DOMAIN OF TCB2, A CALCIUM BINDING PROTEIN FROM TETRAHYMENA THERMOPHILA. Adina M. Kilpatrick , C. Andrew Fowler, Theodore Gurrola, Jerry E. Honts 1039-Pos Board B16 EDUCATION TRAVEL AWARDEE MOLECULAR DYNAMICS STUDY OF DIVALENT ION COORDINATION IN EF HAND PROTEINS. Caitlin E. Scott , Amir N. Kucharski Jr., Peter M. Kekenes- Huskey 1040-Pos Board B17 STRUCTURE AND STABILITY OF TIP LINK CADHERIN-23 FRAGMENTS INVOLVED IN HEARING AND DEAFNESS. Avinash Jaiganesh , Deryanur Kilic, Aniket Patel, Domenic Termine, Florencia Velez-Cortes, Omer Irfan Kufrevioglu, Marcos Sotomayor 1041-Pos Board B18 INTRACELLULAR/SURFACE MOONLIGHTING PROTEINS. Constance Jeffery , Wangfei Wang Protein Stability, Folding, and Chaperones I (Boards B19 - B47) 1042-Pos Board B19 MODELING PEPTIDE VIBRATIONS LOCAL AND PERTURBATIVE CONTRIBU- TIONS. Timothy A. Keiderling , Ahmed Lakhani, Yue Wei, Frank Vazquez, Jan Kubelka, Petr Bour 1043-Pos Board B20 EDUCATION TRAVEL AWARDEE AN IN VITRO INVESTIGATION OF GLOBIN FOLDING AND EXPRES- SION. Premila P. Samuel , William Ou, George N. Phillips Jr., John S. Olson 1044-Pos Board B21 LOSS OF PROTEIN STABILITY DUE TO FORMATION OF INTERMOLECU- LAR DISULFIDE BONDS UNDER THE EFFECT OF OXIDATIVE STRESS: CASE STUDY OF THE RRM2 DOMAIN FROM NEUROPATHOLOGICAL PROTEIN TDP-43. Sevastyan O. Rabdano , Ivan S. Podkorytov, Sergei A. Izmailov, Yulia V. Pivovarova, Alexander P. Yakimov, Tairan Yuwen, Adam Groves, Nikolai R. Skrynnikov 1045-Pos Board B22 DISULFIDE SELECTIVITY UNDER THE CONTROL OF SECONDARY STRUC- TURE IN PROTEIN FOLDING. Kosuke Toyama , Masaki Okumura, Shigeru Shimamoto, Yuji Hidaka 1046-Pos Board B23 DISULFIDE BRIDGES: BRINGING TOGETHER FRUSTRATED STRUCTURE IN A BIOACTIVE PEPTIDE. Yi Zhang , Paramjit Bansal, David Wilson, Klaus Schulten, Norelle Daly, Martin Gruebele 1047-Pos Board B24 CHEMICAL ACCELERATION OF DISULFIDE-COUPLED PROTEIN FOLD- ING. Yuji Hidaka , Takeyosi Nakanishi, Shigeru Shimamoto 1048-Pos Board B25 WHEN ENZYMES AND GREEN SURFACTANTS MEET.  Jens K. Madsen , Jørn D. Kaspersen, Kell K. Andersen, Jan S. Pedersen, Daniel E. Otzen 1049-Pos Board B26 EXPERIMENTAL MEASUREMENT OF THE THERMODYNAMICS UNDERLY- ING THE SURFACE-INDUCED STRUCTURAL CHANGES OF NUCLEIC ACIDS AND PROTEINS. Martin Kurnik , Netzahualcóyotl Arroyo, Hui Li, Di Kang, Kevin W. Plaxco

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