Biophysical Society 60th Annual Meeting

1156-Pos Board B133 KINETICS AND MECHANISM OF FORMATION AND STABILIZATION OF THE RNA POLYMERASE-PROMOTER OPEN COMPEX. Munish Chhabra , Raashi Sreenivasan, Mikaela Poulos, Emily Ruff, Irina Artsimovitch, Tom Record 1157-Pos Board B134 LARGE EFFECTS OF DISCRIMINATOR EXCHANGES ON THE RNA POLY- MERASE-PROMOTER OPEN COMPLEX STRUCTURE, LIFETIME AND TRANSCRIPTION INITIATION PATTERNS. Kate Henderson , Lindsey Felth, Si Wang, Cristen Molzahn, Munish Chhabra, Mikaela Poulos, Emily Ruff, Lauren Bieter, M. Thomas Record Jr 1158-Pos Board B135 EFFECT OF PRESSURE AND TEMPERATURE ON TRANSCRIPTION INITIA- TION IN BACTERIAL CELLS. Khanh Nguyen 1159-Pos Board B136 MEASURING THE DYNAMICS OF TFIIF ON RNA POLYMERASE II BY SMFRET. Wei-hau Chang 1160-Pos Board B137 EFFECT OF FIS ON TRANSCRIPTION-COUPLED DNA SUPERCOILING IN E. COLI. Samantha Dages , Xiaoduo Zhi, Fenfei Leng Ribosomes and Translation (Boards B138 - B147) 1161-Pos Board B138 STRUCTURE AND FUNCTION OF YIDC, AN INSERTASE THAT CHANNELS NEWLY SYNTHESIZED PROTEINS INTO THE CELL MEMBRANE. Rezvan Shahoei , Noah Trebesch, Abhi Singharoy, Klaus Schulten 1162-Pos Board B139 SIMULATING MRNA-TRNA TRANSLOCATION THROUGH THE RIBO- SOME. Kien Nguyen , Paul C. Whitford 1163-Pos Board B140 ERMBL TRANSLATION ON THE RIBOSOME IN THE PRESENCE OF ERYTH- ROMYCIN IS STALLED BY INHIBITION OF PEPTIDE BOND FORMATION. Lars V. Bock , Stefan Arenz, Daniel N. Wilson, Helmut Grubmüller, Andrea C. Vaiana 1164-Pos Board B141 PROGRAMMED -1 FRAMESHIFT OF A RIBOSOME: NON-MONOTONIC VARIATION OF FRAMESHIFT EFFICIENCY WITH INCREASING STIFFNESS OF MRNA SECONDARY STRUCTURE. Bhavya Mishra, Debashish Chowdhury 1165-Pos Board B142 CORRELATED MOVEMENT OF TRNA AND THE RIBOSOME DURING ELON- GATION. Huan Yang , Paul Charles Whitford 1166-Pos Board B143 IDENTIFYING EXPERIMENTAL MEASURES OF INTERSUBUNIT ROTATION IN THE RIBOSOME. Mariana Levi , Kien Nguyen, Liah Dukaye, Paul Charles Board B144 COAXING A VIRAL RNA OUT OF ITS SHELL: HOW DOES A VIRAL RNA GE- NOME INITIATE CONTACT WITH ITS HOST? Richard Sportsman , Christian Beren, Benjamin Kartub, Rees Garmann, WilliamM. Gelbart, Charles M. Knobler 1168-Pos Board B145 EDUCATION TRAVEL AWARDEE NASCENT PROTEINS INTERACT WITH KEY REGIONS OF THE OUTER SUR- FACE OF THE RIBOSOME. AndrewM. Fuchs 1169-Pos Board B146 UNDERSTANDING THE EFFECT OF POST TRANSCRIPTIONAL MODIFICA- TIONS IN THE ANTICODON STEM LOOP OF E.COLI TRNA ARGININE. Sweta Vangaveti , Srivathsan Ranganathan, Kathryn L. Sarachan, Paul F. Agris, Alan Chen, William Cantara Whitford 1167-Pos

1170-Pos Board B147 DYNAMICS OF STOP CODON DISCRIMINATION BY RELEASE FACTOR 1.  Colin D. Kinz-Thompson , Ruben L. Gonzalez, Jr. Protein-Nucleic Acid Interaction I (Boards B148 - B178) 1171-Pos Board B148 PROTEIN SEARCH FOR MULTIPLE TARGETS ON DNA. Maria Kochugaeva , Martin Lange, Anatoly Kolomeisky 1172-Pos Board B149 CATALYTIC MECHANISM OF THE INO80 CHROMATIN REMODELER ACTING ON THE NUCLEOSOME. Marianne Schwarz , Jens Michaelis, Karl-Peter Hopfner 1173-Pos Board B150 EDUCATION TRAVEL AWARDEE HU PROTEIN AND DNA SUPERCOILING DRAMATICALLY ENHANCE LAC- REPRESSOR-MEDIATED DNA LOOPING. Yan Yan , Fenfei Leng, David D. Dunlap, Laura Finzi 1174-Pos Board B151 EXPLORING THE MECHANICS AND DYNAMICS OF GENE SILENCING PRO- TEINS. Haowei Wang , WilliamWiley Navarre, Joshua N. Milstein 1175-Pos Board B152 MOLECULAR SELF-TITRATION AS A MECHANISM OF GENE REGULA- TION. Gregory M.K. Poon , Suela Xhani, Dominique Curtis Stephens 1176-Pos Board B153 DNA-BINDING DYNAMICS OF GLUCOCORTICOID RECEPTOR REVEALED BY PARTICLE IMAGE CORRELATION SPECTROSCOPY. Veer Keizer , Rolf Harkes, Thomas Schmidt, Marcel Schaaf 1177-Pos Board B154 AUTONOMOUS SENSITVITY TO EPIGENETICALLY MODIFIED DNA IS ENCODABLE IN A STRUCTURALLY CONSERVED DNA-BINDING DO- MAIN. Dominique C. Stephens , Gregory M. K. Poon 1178-Pos Board B155 INTEGRATIVE MODELING OF THE ISWI CHROMATIN REMODELING ENZYME FROM CROSS-LINKING/MASS SPECTROMETRY AND SAXS DATA. Christina EM Schindler , Nadine Harrer, Jan Lipfert, Felix Müller- Planitz, Martin Zacharias 1179-Pos Board B156 QUANTITATIVE EXPERIMENTAL ANALYSIS OF THE INFLUENCE OF QUASI- SPECIFIC SITES ON KINETICS OF DNA SCANNING BY THE ZINC-FINGER PROTEIN EGR-1. Catherine A. Kemme , Alexandre Esadze, Junji Iwahara 1180-Pos Board B157 SPATIAL DYNAMICS OF SIRT1 DICTATE METABOLIC TRANSITIONS IN THE CELL NUCLEUS. Suman Ranjit , Lorena Aguilar-Arnal, Chiara Stringari, Paolo Sassone-Corsi, Enrico Gratton 1181-Pos Board B158 EXAMINING TALE PROTEIN BINDING KINETICS AND SITE COMPETITION USING SINGLE MOLECULE IMAGING. Max Kushner , Alexander Van Slyke, Fabio Rinaldi, Avtar Singh, John Lis, Adam Bogdanove, Warren Zipfel 1182-Pos Board B159 A MOLECULE-SCALE VIEW OF THE STRUCTURE AND SPECIFICITY OF THE RNA-GUIDED ENDONUCLEASE CAS9. Eric A. Josephs , D. Dewran Kocak, Christopher J. Fitzgibbon, Joshua McMenemy, Charles A. Gersbach, Piotr E. Marszalek 1183-Pos Board B160 DNA UNWINDING BY CRISPR-CAS9 STUDIED USING SITE-DIRECTED SPIN LABELING. Narin S. Tangprasertchai , Carolina Vazquez Reyes, Xiaojun Zhang, Peter Z. Qin

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