170135_inorganicventures_flipping

1:2 Laying the Founda8on

Stages of a Trace Analysis

A. Planning - Prepare a plan that considers the objec3ve. Planning should begin with a discussion between the analyst and the ini3ator during which all possible problems are defined. The analyst is responsible for method selec3on or development.

B. Sample Collec8on and Storage - Ideally the analyst is involved in this stage, but if not, the analyst should be informed of the sampling procedure at the very least. Sample representa3on and contamina3on issues must be considered.

C. Sample Prepara8on - Contamina3on issues are a major concern during this stage, but not the only concern .

1:3 Laying the Foundation

D. Sample Measurement - The major concerns during this stage are:

• Availability of Cer/fied Reference Materials for method valida/on, plus stable and accurate calibra/on standards, interference standards, and quality control standards.

• Achieving the required precision. It serves no purpose in acquiring a precision that has been reduced to less than one-third of the sampling error. In situa/ons where the sampling error is small and the highest level of precision is required, the analyst faces a difficult task in acquiring precision equivalent to classical wet chemical techniques.

• Obtaining the required sensi/vity and determining the detec/on limit of the measurement.