AOAC ERP MICRO AUGUST 2018

OMAMAN-44 A: Collaborative Study Manuscript Expert Review Panel Use Only August 2018

milk, butter, non-fat dry milk, vanilla ice cream, powdered and liquid infant formula (milk based) 52

containing probiotic, non-probiotic liquid infant formula (soy-based), infant cereal with probiotics, infant 53

rice cereal without probiotic, chicken carcass rinse with neutralized buffered peptone water, chicken 54

carcass rinse with buffered peptone water, and stainless-steel surfaces. 55

( c ) Summary of Validated Performance Claims.— ( 1 ) Performance testing of Heat Processed Milk

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and Dairy Products, Infant Formula and Cereals, stainless steel surfaces and chicken carcass rinses are 57

not statistically different [within the ranges of 95% confidence intervals (CI) log (-0.5, 05) (1, 2, 3, 4)] 58

from mean difference between Peel Plate EB and reference methods, ISO 21528-1:2017 Microbiology of 59

the food chain – Horizontal method for detection and enumeration of Enterobacteriaceae – Part 1: 60

Detection and ISO 21528 ISO 21528-2:2017 Part 2: Enumeration (5, 6). 61

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Definitions

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( a ) Standard Deviation (s r

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). —Standard deviation of replicates for each analyte at each

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concentration of each matrix for each method.

( b ) Log 10

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Mean Difference between Candidate and Reference Methods. ( ) —Mean difference

D

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transformed results with lower and upper 95%

between candidate and reference method log 10

confidence interval (CI) for each analyte at each concentration of each matrix. Differences between 69

methods are considered significant when the CI falls outside (-0.5, 0.5). 70 ( c ) r 2 . —Square of the correlation coefficient of log-log linear regression of studied concentrations. ERP Use Only 71 ( d ) Paired T-Test. —P-value for a 2-tail t-test, p-value <0.05 indicates significance at the 95% 72 confidence level. 73

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