APBI 2016

Less local treatment: where is the limit?

N =361 patients (1991-1998); age 45–75 years pT1pN0M0; GI-II; ER+ Median follow-up of 5.9 years 2x2 clinical trial of factorial design: • +/- radiotherapy & • +/- tamoxifen (2 years)

Winzer K-J, et al. Eur J Cancer. 2004;40:998–1005.