APBI 2016

Fractionations and total doses in APBI

Author/trial

Fractionation

Total dose (Gy)

NSABP B39/RTOG 0413

10 x 4.3 Gy 10 x 3.72 Gy

34.0 37.2 32.0 30.1 36.4 38.5

Perera (2003)

GEC ESTRO (2016)

8 x 4 Gy 7 x 4.3 Gy 7 x 5.2 Gy

EBRT Brachy

Polgár (2010)

NSABP B39/RTOG 0413, IRMA / RAPID

10 x 3.85 Gy

Rodriguez (2013) 3D-CRT

10 x 3.75 Gy 10 x 3.4 Gy 10 x 3.8 Gy

37.5

Chen (2009) 3D-CRT Levin (2012) IMRT

34 38 30 21 30 20 30

Obayomi-Davies (2016) CK Veronesi (2013) electron

5 x 6 Gy 1 x 21 Gy 5 x 6 Gy 1 x 20 Gy 5 x 6 CGE 9 x 4.1 Gy 15 x 2.67

Livi (2015) IMRT Vaidya (2013) X-ray Chang (2013) proton Mozsa (2014) 3D-CRT IMPORT LOW (UK)

36.9 40.0