McKenna's Pharmacology for Nursing, 2e - page 650

638
P A R T 7
 Drugs acting on the reproductive system
■■
Anabolic steroids have been abused to enhance
muscle development and athletic performance, often
with deadly effects.
■■
Anabolic steroids are used to increase haematocrit
and improve protein anabolism in certain depleted
states.
■■
Penile erectile dysfunction can inhibit erection and
male sexual function.
■■
Alprostadil, a prostaglandin, can be injected into the
penis to stimulate erection.
■■
The PDE5 inhibitors are oral agents that act quickly
to promote vascular filling of the corpus cavernosum
and promote penile erection. They differ in duration
and time of onset. They are effective only in the
presence of sexual stimulation.
■■
Dangerous cardiovascular effects, including death,
have occurred when the PDE5 inhibitors are
combined with organic nitrates or alpha-blockers.
Careful teaching is very important to avoid this
drug–drug interaction.
Knowing your strengths and weaknesses helps you to
study more effectively. Take a PrepU Practice Quiz
to find out how you measure up!
ONLINE RESOURCES
An extensive range of additional resources to enhance teaching
and learning and to facilitate understanding of this chapter may
be found online at the text’s accompanying website, located on
thePoint at
These include Watch and
Learn videos, Concepts in Action animations, journal articles,
review questions, case studies, discussion topics and quizzes.
WEB LINKS
Healthcare providers and students may want to consult
the following Internet sources:
Andrology Australia.
Content/national+mens+health-1
Department of Health and Ageing, Australia. National
Male Health Policy.
BIBLIOGRAPHY
Cawley, M. A. (2009). Testosterone replacement therapy: What to
look for, when to treat.
Nurse Practitioner, 34(9)
, 47–52.
Conaglen, H. M. & Conaglen, J. V. (2013). Drug-induced sexual
dysfunction in men and women.
Australian Prescriber, 36(2)
,
42–45.
Farrell, M. & Dempsey, J. (2014).
Smeltzer & Bare’s Textbook of
Medical-Surgical Nursing
(3rd edn). Sydney: Lippincott Williams
& Wilkins.
Goodman, L. S., Brunton, L. L., Chabner, B. & Knollmann, B. C.
(2011).
Goodman and Gilman’s Pharmacological Basis of
Therapeutics
(12th edn). New York: McGraw-Hill.
Kirby, M. (2012). In the balance: Testosterone deficiency and
cardiovascular health.
British Journal of Primary Care Nursing,
9(3)
, 107–109.
McKenna, L. (2012).
Pharmacology Made Incredibly Easy
(1st Australian and New Zealand edn). Sydney: Lippincott
Williams & Wilkins.
McKenna, L. & Mirkov, S. (2014).
McKenna’s Drug Handbook for
Nursing and Midwifery
(7th edn). Sydney: Lippincott Williams
& Wilkins.
Peale, I. (2012). Breaking the silence: Helping men with erectile
dysfunction.
British Journal of Community Nursing, 17(7)
,
310–317.
Porth, C. M. (2011).
Essentials of Pathophysiology: Concepts
of Altered Health States
(3rd edn). Philadelphia: Lippincott
Williams & Wilkins.
Porth, C. M. (2009).
Pathophysiology: Concepts of Altered Health
States
(8th edn). Philadelphia: Lippincott Williams & Wilkins.
Steggall, M. J. (2011). Clinical management of erectile dysfunction.
International Journal of Urological Nursing, 5(2)
, 52–58.
Turkoski, B. B. (2008). Drugs used to treat erectile dysfunction.
Orthopaedic Nursing, 27(3)
, 201–206.
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