C H A P T E R 5 7
Drugs affecting gastrointestinal secretions
915
C H E C K Y O U R U N D E R S T A N D I N G
Answers to the questions in this chapter can be found in
Appendix A at the back of this book.
MULTIPLE CHOICE
Select the best response to the following.
1.
Which of the following would a nurse and midwife
include when describing the action of histamine-2
antagonists to a person?
a.
They block the release of gastrin and pepsin,
leading to a decrease in protein digestion.
b.
They selectively block histamine receptors,
reducing swelling and inflammation at numerous
sites.
c.
They selectively block specific histamine receptor
sites, leading to a reduction in gastric acid
secretion.
d.
They are effective primarily for long-term use
because of their slow onset of action.
2.
H
2
receptors are found throughout the body,
including:
a.
in the nasal passages, upper airways and
stomach.
b.
in the CNS and upper airways.
c.
in the respiratory tract and the heart.
d.
in the heart, CNS and stomach.
3.
Which H
2
antagonist would the nurse expect to be
ordered for a person with known liver dysfunction?
a.
cimetidine
b.
famotidine
c.
nizatidine
d.
ranitidine
4.
The nurse would monitor a person receiving
intravenous cimetidine (
Tagamet
) for an acute ulcer
problem for:
a.
GI upset.
b.
gynaecomastia.
c.
cardiac arrhythmias.
d.
constipation.
5.
Acid rebound is a condition that occurs when:
a.
lowering gastric acid to an alkaline level
stimulates the release of gastric acid.
b.
raising gastric acid levels causes heartburn.
c.
combining protein, calcium and smoking greatly
elevates gastric acid levels.
d.
eating citrus fruit neutralises gastric acid.
6.
A nurse taking care of a person who is receiving a
proton pump inhibitor should teach the person to:
a.
take the drug after every meal.
b.
chew or crush tablets to increase their
absorption.
c.
swallow tablets or capsules whole.
d.
stop taking the drug after 3 weeks of therapy.
7.
Misoprostol (
Cytotec
) is a prostaglandin that is
used to:
a.
prevent uterine contractions.
b.
prevent NSAID-related gastric ulcers in people at
high risk.
c.
decrease hyperacidity with meals and at bedtime.
d.
relieve the burning associated with hiatal hernia
at night.
8.
A nurse or midwife caring for a person receiving
pancreatic enzymes as replacement therapy should
be assessing the person for:
a.
hypertension.
b.
cardiac arrhythmias.
c.
excessive weight gain.
d.
signs of GI irritation.
MULTIPLE RESPONSE
Select all that apply.
1.
People who use antacids frequently can be expected
to experience which of the following adverse effects?
a.
systemic alkalosis
b.
electrolyte imbalances
c.
hypokalaemia
d.
metabolic acidosis
e.
constipation or diarrhoea
f.
muscular weakness
