135
Biophysical Society 58
th
Annual Meeting, San Francisco, California
T
U
E
S
D
A
Y
2434-P
os
B
oard
#B126
UNDERSTANDING THE EVOLUTION OF DYNAMICS FOR AN
INTRINSICALLY DISORDERED PROTEIN.
Daniel R. LaPorte
,
F. Marty Ytreberg
2435-P
os
B
oard
#B127
THE MECHANISM OF AMYLOID-
β
42 FIBRIL ELONGA-
TION.
Thomas Gurry
, Collin M. Stultz
2436-P
os
B
oard
#B128
DIFFERENCES IN DYNAMICS AND STABILITY OF THE WILD
TYPE BETA-AMYLOID A
β
1-40, AND ΔE22-A
β
1-39 (JAPANESE)
MUTANT PROTOFIBRIL STRUCTURES, A MOLECULAR
DYNAMICS STUDY.
Kipp W. Johnson
, Tobin R. Sosnick,
Karl F. Freed, Esmael J. Haddadian
2437-P
os
B
oard
#B129
MODELS OF LENGTH DEPENDENT BEHAVIOR IN
POLYGLUTAMINE BASED ON IMPROVED SIMULATION
METHODS.
Natha R. Hayre
2438-P
os
B
oard
#B130
INFLUENCE OF DESOLVATION BARRIERS IN COUPLED
FOLDING AND BINDING KINETICS OF PKID-KIX.
Talant Ruzmetov,
John J. Portman
2439-P
os
B
oard
#B131
DIFFERENT ROLES OF BACKBONE-ORIGINATED AND
NATIVE-CONTACT-ORIGINATED FLEXIBILITIES OF AN
INTRINSICALLY DISORDERED PROTEIN IN FAST BINDING
AND UNBINDING.
Koji Umezawa
, Jun Ohnuki, Junichi Higo,
Mitsunori Takano
2440-P
os
B
oard
#B132
THE IMPACT OF MOLECULAR DYNAMICS METHODS ON THE
ACCURACY OF SIMULATIONS OF THE DISORDERED PROTEIN
SIC1.
Erik W. Martin
, Tanja Mittag
2441-P
os
B
oard
#B133
ROLEOF INTRINSICHELICITYWITHINN-TERMINAL FLANKING
SEQUENCES ON HUNTINGTIN AGGREGATION MECHA-
NISMS.
Kiersten M. Ruff
, Kanchan Garai, Rohit V. Pappu
2442-P
os
B
oard
#B134
CORRELATION OF HELICAL PROPENSITY IN AMYLIN
SEQUENCES WITH KNOWN AGGREGATION PROPENSITY.
Gül H. Zerze
, Cayla Miller, Jeetain Mittal
2443-P
os
B
oard
#B135
education
travel
awardee
TAU(273-284): A MOLECULAR DYNAMICS STUDY OF
INTRINSICALLY DISORDERED PROTEIN CONFORMATIONS
IN THE PRESENCE OF OSMOLYTES.
Zachary A. Levine
,
Luca Larini, Joan-Emma Shea
2444-P
os
B
oard
#B136
PROTEIN FOLDING AND COLLAPSE: THERMODYNAMICS OF
AGGREGATIONOF GLY
5
VS CONCENTRATION IN SOLUTION.
Deepti Karandur
, Ka-Yiu Wong, B Montgomery Pettitt
2445-P
os
B
oard
#B137
PARSING THE CONTRIBUTIONS OF POLYPEPTIDE
BACKBONES AND SIDECHAINS TO DENATURATION IN
CONCENTRATED AQUEOUS SOLUTIONS OF UREA AND
GUANIDINIUM CHLORIDE.
Alex S. Holehouse
, Nicholas Lyle,
Andreas Vitalis, Devarajan Thirumalai, Rohit V. Pappu
2446-P
os
B
oard
#B138
THE STRUCTURE OF THE
β
-CASEIN PHOSPHOPEPTIDE
CONSISTS OF TWO INDEPENDENT INTRINSICALLY
DISORDERED DOMAINS.
Muhammad A. Naqvi
, Sarah Rauscher,
Régis Pomès, Dérick Rousseau
2447-P
os
B
oard
#B139
MD SIMULATIONTRAJECTORIES OF MULTIPLE INTRINSICALLY
DISORDERED PROTEINS REVEAL ORDER TO DISORDER
TRANSITIONS THAT BEAR FUNCTIONAL SIGNIFICANCE.
Tasneem Ali, Mattaparthi Venkata Satish Kumar, Saurabh Basu,
Rajaram Swaminathan
2448-P
os
B
oard
#B140
PHYSICAL BIOINFORMATICS APPLIED TO INTRINSICALLY
DISORDERED NUCLEOPORIN SEQUENCES REVEALS
UNIVERSAL FUNCTIONAL FEATURES.
David Ando
,
Michael Colvin, Michael Rexach, Ajay Gopinathan
2449-P
os
B
oard
#B141
EXTENSIVE USE OF HOST-MIMICKING MOTIFS SUPPORTS
COMPLEX REGULATION OF VIRAL PROTEINS.
Tzachi Hagai
,
Raul Andino, Madan M. Babu, Ariel Azia
Transcription (Boards #B142–#B166)
2450-P
os
B
oard
#B142
MECHANISM OF TRANSCRIPTIONAL BURSTING IN
BACTERIA.
Shasha Chong
, Chongyi Chen, Hao Ge, X. Sunney Xie
2451-P
os
B
oard
#B143
WATCHING THE RNA POLYMERASE TRANSCRIPTION BY
TIME-DEPENDENT SOAK-TRIGGER-FREEZE X-RAY
CRYSTALLOGRAPHY.
Katsuhiko Murakami
2452-P
os
B
oard
#B144
STRUCTURAL AND DYNAMIC REGULATION OF TFIID-
MEDIATED TRANSCRIPTION INITIATION COMPLEX ASSEM-
BLY BY THE TUMOR SUPPRESSOR P53 PROTEIN. Anna Piasecka,
Lihua Song, Michael Cianfrocco, Vincent Wong, Shenglong Wang,
Joseph Hargitai, William Rice, Eva Nogales, Robert A. Coleman,
Wei-Li Liu
2453-P
os
B
oard
#B145
SINGLE MOLECULE PROBING OF P53’S ABILITY TO
DYNAMICALLY REGULATE CHROMATIN STRUCTURE.
Vincent Wong, Yu-Jen Chen, Charles Kenworthy, Lihua Song,
Gina Dailey, Wei-Li Liu,
Robert A. Coleman
2454-P
os
B
oard
#B146
SUBSTANTIAL NUCLEOTIDE SELECTION PRIOR TO FULL
INSERTION OF THE NUCLEOTIDE IN T7 RNA POLYMERASE
ELONGATION.
Baogen Duan
, Shaogui Wu, Yu Jin
2455-P
os
B
oard
#B147
COMPLETE DISSECTION OF TRANSCRIPTION ELONGATION
REVEALS SLOW TRANSLOCATION OF RNA POLYMERASE II IN
A LINEAR RATCHET MECHANISM.
Manchuta Dangkulwanich
,
Toyotaka Ishibashi, Shixin Liu, Maria L. Kireeva, Lucyna Lubkowska,
Mikhail Kahlev, Carlos J. Bustamante
2456-P
os
B
oard
#B148
LOCALIZATION ANDTRACKING OF SINGLE RNA POLYMERASE
MOLECULES IN LIVE E. COLI.
Somenath Bakshi
, James Weisshaar
2457-P
os
B
oard
#B149
NEXT GENERATION SEQUENCING-BASED PARALLEL
ANALYSIS OF MELTING KINETICS OF 4096 VARIANTS OF
A BACTERIAL PROMOTER. Ewa Heyduk,
Tomasz Heyduk
