viii
Preface
subjected to rigorous scrutiny by the publisher’s excellent
staff throughout the production process. The choice of il-
lustrations, the references listed, the selection of data cited,
and the conclusions expressed reflect the experience and
opinions of the editors and authors. I had the extraordi-
nary opportunity to read all of the new references as well
as to review and edit the manuscripts and pictures of each
chapter.
I have also substantially revised and updated the
Introduction.
Paul P. Rosen, MD
pathologic phenotypic classification presented in this book.
It is possible that the pathology report for a mammary carci-
noma in the coming decade will include a secondary classifi-
cation based on molecular markers. Ultimately, it is genotype
that serves as the basis for phenotype, and the complex, long-
term process of unraveling this relationship will benefit from
the work of investigators familiar with both aspects of mam-
mary disease. Surgical pathologists are uniquely qualified
to fill this role and to assimilate these advances into routine
diagnostic testing for the benefit of patients.
In addition to the extensive revisions and editing of
individual chapters by the authors, this book has been
List of Abbreviations
A list of the most frequently used abbreviations in this book
can be found on page 1351.
LEGENDS FOR COVER IMAGES
Front Cover Image Legends
(clockwise from top left): radial
sclerosing lesion with ductal hyperplasia, cribriform DCIS
(E-cadherin positive) and LCIS (E-cadherin negative) in a
duct, secretory carcinoma, and fluorescence
in situ
hybrid-
ization (FISH) in secretory carcinoma with separated
red
and
green
signals indicating a disrupted
NTRK3
gene. (Courtesy
of Dr. A. John Iafrate and Ms. Clarice Bo-Moon Chang.)
Back Cover Image Legends
(clockwise from top left):
partially infarcted adenomyoepithelioma;
metaplastic carcinoma, spindle and squamous type;
reaction to contents of a ruptured breast implant;
solid papillary carcinoma (arrows indicate fibrovascular cores).
