Ductal Carcinoma
In Situ
369
FIG. 11.50.
Coexistent intraductal and in situ lobular
carcinoma in a single duct-lobular unit.
A,B:
DCIS, apo-
crine type, is present in adenosis on the
right
. LCIS fills
expanded lobular glands on the
left
. Apocrine DCIS is sur-
rounded by LCIS in the
upper left area
. Calcifications are
present in the ductal and lobular
in situ
carcinoma. Apo-
crine DCIS (
right
) associated with LCIS (
left
).
C:
DCIS cells
(
right
) are immunoreactive for E-cadherin, and LCIS cells
(
left
) are not.
A
B
C
FIG. 11.51.
DCIS, high grade.
A:
Solid (“comedo”) carci-
noma. Note mitotic activity.
B:
Papillary carcinoma with
necrosis.
C:
Clear cell carcinoma.
C
