I.
WELCOME AND INTRODUCTIONS
Dawn Frazier welcomed Advisory Panel members and initiated introductions. Darryl Sullivan discussed
with the panel, the goal of the meeting. The goal of the meeting is to identify and/or recommend the
next four (4) priority dietary supplement ingredients.
II.
DISCUSSION ON PRIORITIZING NEXT SET OF INGREDIENTS
A.
INGREDIENT RANKING FEEDBACK
Previously, the Advisory Panel members revised the ranking weight of the Ingredient Ranking
Chart to assist in establishing a method for prioritizing the next set of ingredients. Based upon
the feedback received, Table 1 represents the Ingredient Ranking Charts for the top 10 priority
ingredients as received by American Herbal Products Associations (AHPA), Council for
Responsible Nutrition (CRN), and Herbalife. Each group solicited feedback from their members
and within their organizations. AHPA based its rankings on the average input of AHPA members.
CRN ranked their ingredients on a scale from 5-1 with indications for high and medium
priorities. Herbalife ranked their ingredients based on the need for Standard Method
Performance Requirements (SMPRs) and/or single laboratory validations indicated with either
higher or lower priority levels. Please refer to Table 1.
Table 1
B.
IDENTIFICATION OF NEXT FOUR (4) INGREDIENTS)
Sullivan led the Advisory Panel discussion on identifying and ranking the next four (4) priority
ingredients. There were discussions on safety concerns, USP monographs, and which
ingredients had previous work done (i.e. single laboratory validation studies, expert review
panels, etc.).
AHPA
CRN
Herbalife
1
Ashwagandha (Withania
somnifera)
Lutein and its esters
Aloe
2
Ginseng
Vitamin D
Angelica/ Dong Quai
3
Folin C; two methods:
determination of total
polyphenols and
antioxidant potential
Grape Seed Extract‐
Proanthocyanidines (Polyphenols)
Ashwagandha (Withania somnifera)
4
Turmeric
Pomegranate
Astragalus
5
Ginger
Olive Leaf
Bacopa
6
Lutein
Milk Thistle
Boswellia
7
Bacopa
Phytosterols & (Phytosterol esters) Cinnamon
8
Cinnamon
Folin C; two methods:
determination of total polyphenols
and antioxidant potential
Eleuthero Root
9
Vitamin B6
Cranberry
Ganoderma lucidum
10
Boswellia
Echinacea
Goji (wolfberry or Lycium barbarum)
