Tuesday, October 14, 2014
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9:00 AM – 5:00 PM
Registration/Information
Gandon Central
Session V: Dynamics within Protein Complexes and
Roles in Regulation
Co-Chairs: Brenda Schulman, St. Jude Children’s Research
Hospital, USA & Keith Dunker, Indiana University, USA
9:00 – 9:30 AM
Toby Gibson, European Molecular Biology Laboratory, Germany
Regulation by In-complex Molecular Switching
9:30 – 9:45 AM
Abel Garcia-Pino, Vrije Universiteit Brussels, Belgium*
Entropic Exclusion Determines Allostery in a Major Family of
Intrinsically Disordered Bacterial Transcription Factors
9:45 – 10:15 AM
Jane Dyson, The Scripps Research Institute, USA
Role of Functional Disorder in Large Protein Complexes
10:15 – 10:45 AM
Coffee Break
Gandon South
10:45 – 11:15 AM
Liesbeth Veenhoff, University of Groningen, The Netherlands
Disordered Linker Regions for Sorting of Transmembrane Proteins
11:15 – 11:30 AM
Vincent Hilser, Johns Hopkins University, USA*
Parallel Tuning of Activation and Repression in Intrinsic
Disorder-Mediated Allostery
11:30 AM – 12:00 PM
Susan Taylor, University of California, San Diego, USA
PKA: Dynamic Assembly of Macromolecular Signaling Complexes
12:00 – 3:00 PM
Lunch and Free Time
Session VI: Motifs, Multi-Valency and Membrane-less
Organelles in Cells
Co-Chairs: Peter Tompa, Vlaams Institute of Biotechnology,
Belgium & Peter Wright, The Scripps Research Institute, USA
3:00 – 3:30 PM
Dirk Görlich, Max Planck Institute for Biophysical Chemistry,
Germany
Nup98 FG-Domains from Diverse Species Spontaneously Phase-
Separate into Hydrogels with Exquisite NPC-like Permeability
3:30 – 3:45 PM
Stephanie Weber, Princeton University, USA*
Inverse Size Scaling of the Nucleolus by a Concentration-
dependent Phase Transition
3:45 – 4:15 PM
Tanja Mittag, St. Jude Children’s Research Hospital, USA
The Role of Multivalent Interactions of Tumor Suppressor SPOP
with Gli3 in Regulating Ubiquitination
*Short talks selected from among submitted abstracts
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