Table 29.17-5
Dopamine Receptor Antagonists
Name
Trade (mg)
Capsules
(mg)
Solution
Parenteral
Rectal
Suppositories
(mg)
Adult Dose Range (mg/day)
Generic or
Chemical
Trade
Acute
Maintenance
Chlorpromazine Thorazine 10, 25, 50, 100,
200
30, 75, 150,
200, 300
10 mg/5 mL, 30 mg/
mL, 100 mg/mL
25 mg/mL
25, 100
100–1,600
PO 25–400 IM
50–400 PO
Prochlorperazine Compazine 5, 10, 25
10, 15, 30 5 mg/5 mL
5 mg/mL
2.5, 5, 25
15–200 PO 40–80 IM 15–60 PO
Perphenazine
Trilafon
2, 4, 8, 16
—
16 mg/5 mL
5 mg/mL
—
12–64 PO 15–30 IM 8–24 PO
Trifluoperazine Stelazine
1, 2, 5, 10
—
10 mg/mL
2 mg/mL
—
4–40 PO 4–10 IM 5–20 PO
Fluphenazine
Prolixin
1, 2.5, 5, 10
—
2.5 mg/5 mL,
5 mg/mL
2.5 mg/mL
(IM only)
—
2.5–40.0 PO 5–20 IM 1.0–15.0 PO 12.5–50.0
IM (decanoate or
enanthate, weekly or
biweekly)
Fluphenazine
decanoate
—
—
—
—
2.5 mg/mL
—
—
—
Fluphenazine
enanthate
—
—
—
2.5 mg/mL
—
—
—
—
Thioridazine
Mellaril
10, 15, 25, 50, 100,
150, 200
—
25 mg/5 mL, 100
mg/5 mL, 30 mg/
mL, 100 mg/mL
—
—
200–800 PO
100–300 PO
Mesoridazine
Serentil
10, 25, 50, 100
—
25 mg/mL
25 mg/mL
—
100–400 PO
25–200 IM
30–150 PO
Haloperidol
Haldol
0.5, 1, 2, 5, 10, 20 —
2 mg/5 mL
5 mg/mL (IM
only)
—
5–20 PO 12.5–25 IM 1–10 PO
Haloperidol
decanoate
—
—
—
50 mg/mL,
100 mg/mL
(IM only)
—
25–200 IM (decanoate,
monthly)
Chlorprothixene Taractan
10, 25, 50, 100
—
100 mg/5 mL
(suspension)
12.5 mg/mL
—
75–600 PO
75–200 IM
50–400
Thiothixene
Navane
—
1, 2, 5, 10,
20
5 mg/mL
5 mg/mL (IM
only),
20 mg/mL
(IM only)
—
6–100 PO 8–30 IM 6–30
Loxapine
Loxitane
—
5, 10, 25,
50
25 mg/5 mL
50 mg/mL
—
20–250 20–75 IM 20–100
Molindone
Moban
5, 10, 25, 50, 100 —
20 mg/mL
—
—
50–225
5–150
Pimozide
Orap
2
—
—
—
—
0.5–20
0.5–5.0
IM, intramuscular; PO, oral.
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