Porth's Essentials of Pathophysiology, 4e - page 618

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U N I T 7
Kidney and Urinary Tract Function
thoracic to 3rd lumbar vertebrae (Fig. 24-1). The right kid-
ney normally is situated lower than the left, presumably
because of the position of the liver. In the adult, each kid-
ney is approximately 10 to 12 cm long, 5 to 6 cm wide,
and 2.5 cm deep and weighs approximately 113 to 170 g.
The medial border of the kidney is indented by a deep fis-
sure called the
hilus.
It is here that blood vessels and nerves
enter and leave the kidney. The ureters, which connect the
kidneys with the bladder, also enter the kidney at the hilus.
Gross Structure
The kidney is composed of up to 18 lobes. Each lobular is in
turn composed of nephrons, which are the functional units
of the kidney. Two distinct regions can be identified on
the bisected kidney—an outer cortex and an inner medulla
(Fig. 24-2). The cortex has a reddish-brown granular
appearance that is absent from the medulla. The medulla
consists of light-colored, cone-shaped masses—the renal
pyramids—that are divided by columns of the cortex that
extend into the medulla. Each pyramid, topped by a region
of cortex, forms a lobe of the kidney. The apices of the
pyramids form the papillae (i.e., 8 to 18 per kidney, cor-
responding to the number of lobes), which are perforated
by the openings of the collecting tubules. The renal pelvis
is a wide, funnel-shaped structure at the upper end of the
ureter. It is made up of the calyces or cuplike structures
that drain the upper and lower halves of the kidney.
The kidney is sheathed in a fibrous external capsule
and surrounded by a mass of fatty connective tissue,
especially at its ends and borders. The adipose tissue
protects the kidney from mechanical blows and assists,
together with the attached blood vessels and fascia, in
holding the kidney in place. Although the kidneys are
relatively well protected, they may be bruised by blows
to the loin or by compression between the lower ribs
and the ileum. Because the kidneys are located outside
the peritoneal cavity, injury and rupture do not produce
the same threat of peritoneal involvement as that of
other organs such as the liver or spleen.
Renal Blood Supply
Each kidney is supplied by a single renal artery that
arises on either side of the aorta. As the renal artery
approaches the kidney, it divides into segmental arteries
that enter the hilus of the kidney. In the kidney, each seg-
mental artery branches into several lobular arteries that
Left kidney
Renal
vein
Renal
artery
Aorta
Ureter
Bladder
Urethra
Inferior
vena cava
Right
kidney
Adrenal
gland
Diaphragm
T11
T12
FIGURE 24-1.
Kidneys, ureters, and bladder. (The right kidney
is usually lower than the left.)
Pyramid
Renal
cortex
Renal column (Bertin)
Calyx (cut edge)
Calyx
Capsule
Ureter
Renal artery
Renal pelvis
Renal blood vessel
Renal medulla
Renal papillae
Hilus
FIGURE 24-2.
Internal structure of the kidney.
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