C h a p t e r 2 7
Disorders of the Bladder and Lower Urinary Tract
673
R E V I EW E X E R C I S E S
1.
A 23-year-old man is recovering after the acute
phase of a cervical (C6) spinal cord injury with
complete loss of motor and sensory function
below the level of injury. He is now experiencing
spastic bladder contractions with involuntary and
incomplete urination. Urodynamic studies reveal
spastic contraction of the external sphincter with
urine retention and high bladder pressures.
A.
Explain the reason for the involuntary urination
and incomplete emptying of the bladder despite
high bladder pressures.
B.
What are possible complications associated with
overdistention and high pressure within the
bladder?
2.
A 66-year-old woman complains of leakage of
urine during coughing, sneezing, laughing, or
squatting down.
A.
Explain the source of this woman’s problem.
B.
One of the recommended treatments for stress
incontinence is the use of Kegel exercises, which
focus on strengthening the muscles of the pelvic
floor. Explain how these exercises contribute
to the control of urine leakage in women with
stress incontinence.
3.
A 26-year-old woman makes an appointment with
her health care provider, complaining of urinary
frequency, urgency, and burning. She reports that
her urine is cloudy and smells abnormal. A urine
dipstick indicates the presence of infection, a urine
sample is obtained for culture, and she is given a
prescription for antibiotics.
A.
What microorganism is most likely responsible
for the infection?
B.
What factors may have predisposed her to this
disorder?
C.
What could this woman do to prevent future
infection?
R E F E R E N C E S
1. Tanagho EA, Lue TF. Anatomy of the genitourinary tract.
In: McAninch JW, Lue TF, eds.
Smith and Tanagho’s General
Urology
. 18th ed. New York, NY: McGraw-Hill Medical;
2013:1–16.
2. Hall JE.
Guyton and Hall Textbook of Medical Physiology
. 12th
ed. Philadelphia, PA: Saunders Elsevier; 2011:307–310.
3. Ross MH, Pawlina W.
Histology: A Text and Atlas
. 6th ed.
Philadelphia, PA: Wolters Kluwer Health/Lippincott Williams &
Wilkins; 2011:723–725.
4. Birder LA, Ruggieri M, Takeda M, et al. How does the
urothelium affect bladder function in health and disease.
Neurourol Urodyn.
2012;31(3):293–299.
5. Anderson K-E. Neurophysiology and pharmacology of the
lower urinary tract. In: McAninch JW, Lue TF, eds.
Smith and
Tanagho’s General Urology
. 18th ed. New York, NY: McGraw-
Hill Medical; 2013:429–441.
6. Clemens JQ. Basic bladder neurophysiology.
Urol Clin North
Am.
2010;37:487–494.
7. Lue TF, Tanagho EA. Neuropathic bladder disorders. In: McAninch
JW, Lue TF, eds.
Smith and Tanagho’s General Urology
. 18th ed.
New York, NY: McGraw-Hill Medical; 2013:442–457.
8. Tanagho EA, Bella AJ, Lue TF. Urinary incontinence. In:
McAninch JW, Lue, TF, eds.
Smith & Tanagho’s General
Urology
. 18th ed. New York, NY: McGraw-Hill Lange;
2013:489–497.
9. Porten SP, Greene KE. Urologic laboratory examination. In:
McAninch JW, Lue TF, eds.
Smith & Tanagho’s General Urology
.
18th ed. New York, NY: McGraw-Hill Lange; 2013:48–60.
10. Tanagho EA, Lue, TF. Urinary obstruction and stasis. In:
McAninch JW, Lue TF, eds.
Smith and Tanagho’s General
Urology
. 18th ed. New York, NY: McGraw-Hill Lange;
2013:170–181.
11. Seliu BA, Subedi R. Urinary retention in adults: diagnosis and
initial management.
Am Fam Physician.
2008;77(5):643–650.
12. Dorsher PT, McIntosh PM. Neurogenic bladder.
Adv Urol.
2012:1–16.
13. Jeong AJ, Cho CY, O S-J. Spinal cord injury and the neurogenic
bladder.
Urol Clin North Am.
2010;37:S37–S46.
14. Sasaki K, Yoshimura N, Chancellor MB. Implication of diabetes
mellitus in urology.
Urol Clin North Am.
2003;30:1–12.
15. Vinik AI, Maser RE, Mitchell BD, et al. Diabetic autonomic
neuropathy.
Diabetes Care.
2003;26:1553–1579.
16. Sampselle CM, Palmer MH, Boyington AR, et al. Prevention
of urinary incontinence in adults.
Nurs Res.
2004;53(6
suppl):S61–S67.
17. Lue FT. Urinary incontinence. In: McAninch JW, Lue TF, eds.
Smith and Tanagho’s General Urology
. 18th ed. New York, NY:
McGraw-Hill Lange; 2013:180–497.
18. Abrams P, Anderson KE, Birder L, et al. Fourth International
Consultation on Incontinence Recommendations of the
International Scientific Committee: evaluation and treatment
of urinary incontinence, pelvic organ prolapse, and fecal
incontinence.
Neurourol Urodyn.
2010;29:213–240.
19. Fong E, Nitti VW. Urinary incontinence.
Prim Care.
2010;37:599–612.
20. Khandelwal C, Disterler C. Diagnosis of urinary incontinence.
Am Fam Physician
. 2013;87(8):543–550.
21. Yoshimura N, Miyazato M. Neurophysiology and therapeutic
receptor targets for stress urinary incontinence.
Int J Urol.
2012;19:524–537.
22. Deng DY. Urinary incontinence in women.
Med Clin North Am.
2011;95:101–109.
23. Smith PP, McCrery RJ, Appell RA. Current trends in the
evaluation and management of female urinary incontinence.
Can
Med Assoc J.
2006;175:1233–1240.
24. Carpenter DA, Visovsky C. Stress urinary incontinence: a review
of treatment options.
AORN J.
2010;91(4):471–478.
25. Hayden RT, deRidder D, Freeman RM, et al. An International
Urogynecological Association (IUGA) International Continence
Society (ICS) joint report on the terminology for female pelvic
floor dysfunction.
Neurourol Urodyn.
2010;29:4–20.
26. Banackhar MA, Al-Shaiji TF, Hassouna MM. Pathophysiology of
overactive bladder.
Int Urogynecol J.
2012;23:975–982.
27. Chu FM, Dmochowski R. Pathology of overactive bladder.
Am J
Med.
2006;119(suppl 3A):3S–8S.
28. Nygaard I. Idiopathic urgency urinary incontinence.
N Engl J
Med.
2010;363(32):1156–1162.
29. Ouslander JG. Management of overactive bladder.
N Engl J Med.
2004;350:786–799.
30. Gibbs CF, Johnson TM, Ouslander JG. Office management of
geriatric urinary incontinence.
Am J Med.
2007;120:213–220.