Advanced Physics for Brachytherapy 2018

Examples for setup uncertainties in BT:

Prostate : Variations of target dose during HDR treatment due to catheter and gland movement

Gyn : Mean DVH shifts (%) due to uncertainties in tandem/ring applicator position (mm) (reconstruction or movement)

7

lateral ant-post longitudinal rotation

Hoskin et al. 2003, Radiother Oncol 68

6

Breast : variations of maximum skin dose and high dose volumes of breast tissue (Mammo Site applicator)

5

4

3

2

% pr. mm displacement 0 1

GTV HR-CTV Rectum Bladder Sigmoid

Tanderup et al. 2008, Radiother Oncol 89

Kim Y. et al 2008, IJROBP 71