Advanced Physics for Brachytherapy 2018

Monte Carlo for TPS? ➢ t CALC

reductions from: photon only tracking (20%-70%), track length scoring (20- 30), pre-calculated source phase space (30%-40%), variance reduction (40-60) + (inherent) parallelization and reduction of t CALC /N from availability of multi-core processors have facilitated clinically viable calculation times : ✓ sub-minute to minutes for LDR applications MCPI (GEPTS): Chibani & Williamson 2005 Med Phys 32, 3688 BRACHYDOSE (EGSnrc): Thomson et al 2010 Med. Phys. 37, 3910 ALGEBRA (GEANT4): Afsharpour et al. 2012 Phys Med Biol 57, 3273 ✓ 2.5–17 minutes for 40 3 –140 3 2mm voxels for HDR rectal application BRACHYGUI (PTRAN) Poon et al 2008 J Phys Conf Ser 102, 012018.

➢ further reduction of of t /N from GPU implementation : ✓ Tian et al, “Monte Carlo dose calculations for high-dose–rate brachytherapy using GPU-accelerated processing,” Brachytherapy 15(3), pp. 387 (2016). CALC