Advanced Physics for Brachytherapy 2018

LQ Model

2 D D E  +  = b

a

Biological effect E of dose D:

Total dose :

D

dn  =

n... Nr. of fractions, d... fraction dose

2

( nd d d nE ) b a b d

(

a

)

= + = +  =

d

nd

a

1(

) + =

a

/

b

= E = a x

total dose x

relative dose effectiveness

Biologically effective dose: BED = total dose x relative dose effectiveness = E / a

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