Advanced Physics for Brachytherapy 2018

Inverse Optimisation and Planning: Topography based (TOP)

▪ “..local History”: Pre-delivered Dose Part of Implant

N



 x

1

i





(

)

p

( )

( )

i L

i

i L

i

1  = j

x − −  =

f

d D d D

i

j

j

N

i

d i

j (x) has a “History”.

N





1

i

) ( )  x − −  = i i H  H j

( ) ( x i

p i

1  = j

f

D d D d

i

j

N

i

“History”:

• Pre-delivered Dose (previous Implants or ERT)

• Fixed contribution of a part of the implant

(Fixed contribution form Ring + Tandem & TOP

of

additional interstitial needles)

* Using HIPO (Pi-Medical Ltd) implementation in Oncentra Prostate & Oncentra Brachy (Elekta, Nucletron B.V.)