207_Combined course Presentations

Basket trials matching patients to therapies based on molecular profiles

Lead organizatio n

Primary outcome measure(s) TMA (screening) TMA (screening) TMA (screening)

Clinicaltrial s.gov identifier NCT017239 69 NCT022141 34 NCT023076 04

Program name

# Expected to accrue

Design Histology Indication

Advanced colorectal cancer Thoracic tumors Brain neoplasms BRAF V600E - mutated advanced solid tumors

SPECTA EORTC NR

Metastatic 2,600

Any stage 3,500

Any stage 300

Hoffmann- La Roche

NCT015249 78

VE-BASKET

NR

Metastatic 160

ORR