207_Combined course Presentations

Best Tumor Shrinkage of Patients Enrolled in Genotype-Matched Trials

RECIST v1.1 Overall Response Rate= 20%

Breast

Genotype Matched Trials Most Common Mutations

Colorectal

Disease Sites

Lung Gynecological Genitourinary Pancreatobiliary

Breast

22 18 21 22

PIK3CA (18)

Colorectal

BRAF (8), KRAS (5) KRAS (11), EGFR (8) KRAS (12), PIK3CA (6)

Upper Aerodigestive Other

Lung

Gynecological

P. Bedard et al. AACR 2015