207_Combined course Presentations

AXL-Axis: Additional Modes of Action

AXL immunosuppresses innate immune cells

AXL is expressed in immunosuppressive cells

AXL drives immunosuppressive cytokine release

AXL expression inhibits NK cell mediated anti-metastatic effects

AXL promotes vasculogenesis

AXL is overexpressed in EGFR-treatment resistant tumors

(Several Met inhibitors inhibit AXL)