207_Combined course Presentations
National or institutional molecular screening programs in breast cancer and other advanced solid tumors predictive biomarker
Institution or National Program
Platform
Cancer(s)
Archival vs Biopsy
Timeframe
Additional Details
Massachusetts General Hospital
SNaP Shot
NSCLC, CRC, Melanoma, Breast
Archival
Ongoing
Includes somatic mutations in 14 oncogenes. In NSCLC, additional FISH panel for ALK rearrangements. Plan to integrate NGS technology in near future. $43 million investment over 5 years. Currently tests ~470 mutations in 41 genes. “T9 Program”. Customized Sequenom Panel (40+ genes) with Sanger confirmation.
Dana Farber Cancer Institute
OncoMap (Sequenom)
All solid tumors
Archival
Ongoing
MD Anderson Cancer Centre
Sequenom
All
Archival
Ongoing
Plan to screen “Ten Thousand Tumors”.
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