207_Combined course Presentations

New agents

• 4 main types

– PI3K inhibitors e.g. BKM120 – AKT inhibitors e.g. AZD5363, perfosine – mTOR complex 1/2 inhibitors e.g. everolimus, ridoforolimus, metformin, AZD8055 – Dual mTOR/PI3K inhibitors, e.g. XL765