207_Combined course Presentations

Primary end-point [n=515]

R0 resection rates (surgery performed & pathologic R0 status): 77% for SCPRT with 3 cycles of chemotherapy 71% for CRT (control arm) (p=0.081)

Secondary end-points

SCRTx + FOLFOX4

CRTx

P value

Overall acute toxicity Grade III/IV toxicities

75%

83% p= 0.006

23%

21%

NS

pCR rate

16%

12%

p= 0.17