207_Combined course Presentations

d-HER2 induces antibodies that specifically bind the native HER2 receptor • The ECD binding ratio seems to increase with the dose of HER2 protein when assessed after the administration of four dHER2 + AS15 doses.

100

SKBR3

BT474

80

60

Day 0 Day 56

Day 0 Day 56

%

40

20

0

Cohort 1 Cohort 2 Cohort 3 Cohort 4

A

B

C

G. Curigliano et al. 2016