207_Combined course Presentations

EGFR overexpression in human tumors

Tumors showing high EGFR expression

•

NSCLC

40-80%

High expression generally associated with • Invasion • Metastasis • Late-stage disease

•

Prostate

40-80%

•

Gastric

33-74%

•

Breast

14-91%

•

Colorectal

25-77%

•

Pancreatic

30-50%

•

Ovarian

35-70%

•

Chemo-/Radiotherapy resistance

•

Bladder

31-48%

•

Renal cell

50-90%

•

Poor outcome

•

H&N

80-100%

•

Glioma

40-63%

•

Esophageal 43-89%