207_Combined course Presentations

CODEL: Phase III study of RT+ concomitant and adjuvant TMZ vs RT + adjuvant PCV in patients with 1p/19q codeleted anaplastic glioma or Low grade glioma

INITIAL DESIGN PROPOSED DESIGNED OF REVITALIZED TRIAL

RT

followed by PCV x 6

Central pathology - O/AO

R

TMZ

- 1p/19q codeletion

RT + TMZ followed by adjuvant TMZ x 6

Estimated enrollment: 520 Study start date: October 2009 Estimated primary completion date: December 2018