207_Combined course Presentations

Summary

True RT-induced abscopal effects exist, are rare, are immune- mediated (irradiated tumor as immunogenic hub)  Novel immunomodulatory agents have the potential to maximise RT-induced anti-tumor immune responses  Radiotherapy can enhance antitumor immune response Multiple questions exist: Relation between dose/fraction and the immune effects of radiation; additional resistance mechanisms Timing of immune therapy with radiotherapy is crucial

Is R ejection of neoplastic lesions by immune system a novel « R »?