207_Combined course Presentations

“Concomitant” is better than “Sequential” Radio-Chemotherapy



Absolute

survival benefit

with

concomitant radio-chemotherapy:

5.7% at 3 years

•

4.5% at 5 years

•



Concomitant radio-chemotherapy

increased acute esophageal toxicity

(Grade 3-4) from 4% to 18% with a

relative risk of 4.9 (p < 0.001).

There was no significant difference

regarding acute pulmonary toxicity

Aupérin A, et al. JCO 2010;28