Physics Bucharest 2017

Five serial planning CTs, with varied filling of urinary catheter and rectal balloon; planning CT scan at 20 fractions Cine-MRI over 20mins pre-RT, repeated after week 4 Cine-MRI over 28mins at staging, 2-3 weeks later prior to RT

Fokdal et al., (2004)

15

2.4 1.1 3.5 0.5 1.3

87%

89% (78%, 95% confidence interval maximum displacement <1.5 cm)

Manger et al., (2007)

9

1.5 isotropic

McBain et al., (2009)

50% at 14mins with 1.5cm margin

15

1.5-2.0 isotropic

Lalondrelle et al., (2011)

Planning CT 0 (CT0), 15, 30mins, pre-RT CBCT (CTVcb), post RT CBCT,

1.5 (CTV0), 0.5 (CTVcb)

49% of fractions (51% of pre-RT outside CT0)

15

63% with population based margin (3 out of 8 patients did not have bladder encompassed by PTV; bladder volume coverage in these patients was 98.1%- 99.9%)

Planning CT, pre-RT CBCT, weekly post RT CBCT, MRI scan pre-treatment, weekly at 0, 2, 4, 6, 8,10mins

Gronberg et al., (2015)

1.4 1.4 0.9 0.5 0.5 .4 0 9 1.4 0.5

9

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