Physics Bucharest 2017

Adaptive planning solutions

Plan of the day

Library of plans based on i)Variable margins around empty bladder

Planning CT

i)Patient's own bladder filling (and variable margins)

variable margin used to create 3 PTV contours ( small , medium , large ) from which library of 3 plans created

Hafeez S et al: Prospective Study Delivering Simultaneous Integrated High-dose Tumor Boost (≤70 Gy) With Image Guided Adaptive Radiation Therapy for Radical Treatment of Localized Muscle-Invasive Bladder Cancer. International Journal of Radiation Oncology*Biology*Physics 2016, 94(5):1022-1030. Lalondrelle S, et al. Adaptive-predictive organ localization using cone-beam computed tomography for improved accuracy in external beam radiotherapy for bladder cancer. Int J Radiat Oncol Biol Phys 2011, 79(3):705-712. McDonald F et al: Clinical implementation of adaptive hypofractionated bladder radiotherapy for improvement in normal tissue irradiation. Clin Oncol (R Coll Radiol) 2013, 25(9):549-556