Physics Bucharest 2017

Adaptive planning- head and neck model

• We usually adapt to changes in morphology of tumor and OAR’s. • Provoking factors : weight loss, tumor response, progression of disease Hansen et al. • evaluated the impact of replanning in a cohort of 13 HNC patients with either significant weight loss or tumor response during IMRT. • Compared to replanning, not replanning significantly decreased dose to the target volume and increased doses to normal tissues (spinal cord and brainstem). The doses to 95% of the PTV-GTV and the PTV-CTV decreased by up to 6.3 Gy and 7.4 Gy, respectively.