Physics Bucharest 2017

HDR vs. LDR in prostate cancer

May be radiobiological advantage of HDR over LDR if prostate α/β ratio is low

HDR Equipment already available in most departments and less costly

HDR may have fewer issues with QA: mis-placement of LDR seeds results in poor quality implants

Toxicity profile may be more favourable (shorter duration)

Randomised trial of external beam radiotherapy alone or combined with high-dose-rate brachytherapy boost for localised prostate cancer Peter J. Hoskin et al. RO 2012; 103(2):217-22.