Physics Bucharest 2017

Latency in appearance of radiation-induced tumors

Challenge in epidemiological studies

 many (known and unknown) reasons why people get a cancer.  most second tumors are not induced by RT  Boice 1985 : 68.730 irradiated cervical cancer patients with > 1 year follow-up, 3.324 (4.8%) second cancers, 162 ( 4.9 % ) could be attributed to RT (162 = 0.24% of total number).  detect small number of RT-induced tumors on top of large unknown baseline of non RT-induced tumors

Clinical data

32