Physics Bucharest 2017

Final remarks

 this is not more than an introduction, see Bibliography for further reading  important ommission: how to deal with tumor deformations  establish Σ( j ) and σ( j ) for various parts j of the tumor and use M(j)=2.5Σ (j ) +0.7 σ( j )  Monte Carlo simulations including models for non-rigid motion derived for multiple CT-scans per patients: Mutanga et al 2012  If tumor moves then also surroundig tissues move: omit margins and incorporate motion distributions for tumor and OAR in cost functions for IMRT optimization (robust planning)  IT ALL STARTS WITH MEASURING ERRORS!!!