Physics Bucharest 2017

M (distant spread)

• Spread to areas of the body distant or remote from the primary tumor. • Distant metastases are comprised of tumor cells which have broken away from the primary tumor and have traveled to other organs. • Also called remote, disseminated, diffuse, metastatic. • Methods of spread: • Travel in lymph channels beyond the first drainage area • Hematogenous or blood-borne metastases • Spread through fluids in a body cavity