Physics Bucharest 2017

Hyperfractionation (HF)(<1.8 Gy per fraction)

CF

HF

70Gy, 2.0 Gy, 7w

80.5Gy, 2 x 1.15 Gy, interval = 6h, 7w

Expectations (dose-escalated HF): • Increased tumor control • More severe early reactions • Unchanged or less late reactions