Physics Bucharest 2017

Moderate hypo-fractionation in prostate RT (<4Gy/fx)

With 3Gy x 20 delivered daily using IMRT 1. Acute GI toxicity peaks earlier and higher but resolves quicker 2. Acute GU toxicity peaks earlier but resolves quicker 3. No difference noted in late toxicity Note: HYPRO study  toxicity with 3.4Gyx19 3 times per week

Dearnaley et al. and Incrocci et al Both Lancet Oncology 2016 DOI.org/10.1016/S1470-2045