Physics Bucharest 2017

Craniospinal irradiation

Medulloblastoma

• Primitive neuro-ectodermal tumour which arises most commonly in the cerebellum • Most common primary CNS tumour in children (20%) but uncommon in adults (0.5 cases per 100,000)

• Most commonly arises in the posterior fossa – Spread commonly in craniospinal axis – Systemic metastasis is uncommon but reported – Presenting symptoms:  Hydrocephalus related symptoms  Cerebellar symptoms  Leptomeningeal symptoms