Physics Bucharest 2017

RCC/Melanoma

Metastastic pts with “radioresistant” tumors: -17 melanoma pts – 28 lesions -13 RCC pts – 25 lesions Lung > liver > bone mets Dose: 3-5 fr; 40-60 Gy No severe toxicity (sorafenib, sutinib...) Median fup: 28 m

90%

Ex. BED 5 x 8 Gy 72 Gy 3 x 20 Gy 180 Gy 3 x 16 Gy 125 Gy

Clinical indications

126 Gy

46

Stinauer Radiat Oncol 2011