CROI 2015 Program and Abstracts

Poster Listings

Session P-L3 Poster Session

Poster Hall

606 High Rates of Early Virologic Failure in a Cohort of Tanzanian HIV- Infected Adults Claudia A. Hawkins 1 ; Nzovu Ulenga 2 ; Enju Liu 3 ; Said Aboud 4 ; Ferdinand Mugusi 4 ; Guerino Chalamilla 2 ; David Sando 2 ; Eric Aris 2 ;Wafaie Fawzi 3 1 Northwestern University, Feinberg School of Medicine, Chicago, IL, US; 2 Management and Development for Health, Dar es Salaam, United Republic of Tanzania; 3 Harvard School of Public Health, Boston, MA, US; 4 Muhimbili University of Health and Allied Sciences, Dar es Salaam, United Republic of Tanzania 607 HIV Drug Resistance Surveillance in Honduras After 10 Years of Widespread ART Claudia Garcia-Morales 1 ; Santiago Avila-Rios 1 ; DanielaTapia-Trejo 1 ; Rita Meza 2 ; Sandra Nuñez-Rubio 2 ; Norma Flores 5 ;Wendy Murillo 3 ; Ivette Lorenzana 3 ; Elsa Palou 4 ; Gustavo Reyes-Terán 1 1 National Institute of Respiratory Diseases, Mexico City, Mexico; 2 Honduran HIV National Program and National Laboratory, Tegucigalpa, Honduras; 3 Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras; 4 Hospital Escuela Universitario, Tegucigalpa, Honduras; 5 Instituto Nacional Cardiopulmonar, Tegucigalpa, Honduras 608 High Prevalence of Genotypic Resistance to Integrase inhibitors of HIV-1 Strains in Taiwan Sui-Yuan Chang 1 ; Chien-Ching Hung 2 1 National Taiwan University, Taipei, Taiwan; 2 National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan 609 Integrase Resistance Correlates of Response to Dolutegravir (DTG) Through 48Weeks Cindy L. Vavro ; Jenny Huang; Mounir Ait-Khaled GlaxoSmithKline, Research Triangle Park, NC, US 610 Discordant Predictions Could Impact Dolutegravir Use Upon Raltegravir Failure Kristof Theys 1 ; Ana B. Abecasis 2 ; Pieter Libin 1 ; Perpétua Gomes 2 ; Joaquim Cabanas 3 ; Ricardo J. Camacho 1 ; KristelVan Laethem 1 the Portuguese HIV-1 Resistance Study Group 1 University of Leuven, Leuven, Belgium; 2 Universidade Nova de Lisboa, Lisbon, Portugal; 3 Hospital Egas Moniz, Lisbon, Portugal 611 Integrase S119P Mutation Correlates With Disease Progression in HIV-1 Naïve Patients Daniele Armenia 1 ; Maria Mercedes Santoro 1 ; Caterina Gori 2 ; Emanuele Nicastri 2 ; Antonio Cristaudo 3 ; Massimo Andreoni 4 ; Andrea Antinori 2 ; Zeger Debyser 5 ; Carlo-Federico Perno 2 ; Francesca Ceccherini-Silberstein 1 1 University of Rome Tor Vergata, Rome, Italy; 2 L. Spallanzani Hospital, Rome, Italy; 3 San Gallicano Dermatological Institute, Rome, Italy; 4 University Hospital Tor Vergata, Rome, Italy; 5 Katholieke Universiteit Leuven, Leuven, Belgium 2:30 pm– 4:00 pm Nucleic-Acid–Based Detection of HIV 612 A Generalized Entropy Measure of Viral Diversity for Identifying Recent HIV-1 Infections JuliaW. Wu ; Oscar Patterson-Lomba; Marcello Pagano Harvard School of Public Health, Boston, MA, US 613 Acute Infections, Cost and Time to Reporting of HIV Test Results in US State Public Health Laboratories MuazzamNasrullah 1 ; Laura G.Wesolowski 1 ; Steven F. Ethridge 1 ; Kevin Cranston 2 ; Robert A. Myers 3 ; JamesT. Rudrik 4 ; Angela B. Hutchinson 1 ; Barbara G.Werner 2 1 US Centers for Disease Control and Prevention (CDC), Atlanta, GA, US; 2 Massachusetts Department of Public Health, Boston, MA, US; 3 Maryland Department of Health and Mental Hygiene, Baltimore, MD, US; 4 Michigan Department of Community Health, Lansing, MI, US TUESDAY, FEBRUARY 24, 2015 Session P-M1 Poster Session Poster Hall

2:30 pm– 4:00 pm Transmitted HIV Drug Resistance: Assessing the Threat 598 Large NNRTI-Resistant Transmission Cluster in Injection Drug Users From Saskatchewan Alexander Wong 1 ; Jaspreet Kambo 1 ; Richard Harrigan 2 ; Art F. Poon 2 ; Jeffrey B. Joy 2 1 University of Saskatchewan, Regina, Canada; 2 BC Centre for Excellence in HIV/AIDS, Vancouver, Canada 599 Transmitted Drug Resistance and Time of HIV Infection, New York State, 2006-2013 ZhengyanWang 1 ; EmilyWalits 2 ; Daniel E. Gordon 1 ; Bridget J. Anderson 1 ; Deepa Rajulu 1 ; LingWang 1 ; Lou C. Smith 1 1 New York State Department of Health, Albany, NY, US; 2 University at Albany, School of Public Health, Albany, NY, US 600 Transmitted HIV Drug Resistance Among Early Infected Persons in San Diego, California Theppharit Panichsillapakit 1 ; David M. Smith 2 ; JoelWertheim 2 ; Douglas D. Richman 2 ; Susan Little 2 ; Sanjay Mehta 2 1 Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; 2 University of California San Diego (UCSD), La Jolla, CA, US 601 HIV Molecular Epidemiology and Transmitted Drug Resistance in the Mesoamerican Region Claudia Garcia-Morales 1 ; Santiago Avila-Rios 1 ; DanielaTapia-Trejo 1 ; Carlos Mejía- Villatoro 2 ; Juan M Pascale 3 ; Guillermo Porras-Cortes 5 ; Ivette Lorenzana 4 ; Elsa Palou 4 ; Marvin Manzanero 6 ; Gustavo Reyes-Terán 1 1 National Institute of Respiratory DIsease, Mexico City, Mexico; 2 Roosevelt Hospital, Guatemala City, Guatemala; 3 Gorgas Memorial Institute for Health Studies, Panama City, Panama; 4 Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras; 5 Vivian Pellas Metropolitan Hospital, Managua, Nicaragua; 6 Ministry of Health, Belize City, Belize 602 Temporal Trends of Transmitted HIV Drug Resistance Following Seroconversion Ashley Olson 1 ; Claudia Kucherer 3 ; Anders Sönnerborg 4 ; Carmen de Mendoza 5 ; Robert Zangerle 6 ; Maria Prins 9 ; John Gill 2 ; Anne-Marte Bakken Kran 7 ; Dimitrios Paraskevis 8 ; Kholoud Porter 1 for CASCADE collaboration in EuroCoord 1 University College London, London, United Kingdom; 2 University of Calgary, Alberta Health Services, Calgary, Canada; 3 Robert Koch Institute, Berlin, Germany; 4 Karolinska Institutet, Stockholm, Sweden; 5 Puerta de Hierro Research Institute and University Hospital, Madrid, Spain; 6 Innsbruck Medical University, Innsbruck, Austria; 7 Oslo University Hospital, Oslo, Norway; 8 University of Athens, Athens, Greece; 9 Public Health Service of Amsterdam, Amsterdam, Netherlands 603 Increase in HIV Primary Drug Resistance in a Demographic Surveillance Area in Rural KwaZulu-Natal South Africa Justen Manasa; Siva Danaviah; FrankTanser; Sureshnee Pillay; Hloniphile Mthiyane; Eduan Wilkinson; Deenan Pillay; Tulio de Oliveira University of KwaZulu-Natal, Durban, South Africa Session P-L4 Poster Session Poster Hall 2:30 pm– 4:00 pm HIV Drug Resistance: Global Perspective and Clinical Implications 604 A Clinical Prediction Rule for PI Resistance in Resource-Limited Settings Karen Cohen 1 ; Annemie Stewart 1 ; Andre P. Kengne 1 ; Rory F. Leisegang 1 ; Marla Coetsee 2 ; Shavani Maharaj 2 ; Liezl Dunn 2 ; Graeme Meintjes; Gert U. van Zyl 3 ; Gary Maartens 1 1 University of Cape Town, Cape Town, South Africa; 2 Aid for AIDS Management (Pty) Ltd, Cape Town, South Africa; 3 University of Stellenbosch, Cape Town, South Africa 605 Baseline Low-Frequency HIV-1 Variants Do Not Predict Virologic Failure to RPV/FTC/TDF Danielle P. Porter 1 ; Martin Däumer 2 ; AlexanderThielen 2 ; Michael D. Miller 1 ; Kirsten L. White 1 1 Gilead Sciences, Inc., Foster City, CA, US; 2 Seq-IT GmbH & Co KG, Kaiserslautern, Germany

Poster Listings

49

CROI 2015