Lower GI 2017

Limitations and Critical Points

Polish Trial

Trans-Tasman

Small

• Small (powered for 15% diff.) • Sphincter Preserv. dependent

•

• Local control: 10 % difference? • MRI staging not mandatory

on surgical commitment

Lack of info on MRF

• Poor compliance of CRT (69%) • Imbalance in adjuvant CTx (46 vs 30% after CRT) • No central quality control

•

Lack of info on TME, CRM

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• Imbalance in tumor location (10% more low tumors in SCRT)