Lower GI 2017

HDR-EBT – Conclusions

1. HDR-EBT delivers a high dose to the tumor and a limited dose to surrounding

normal tissues

2. In resectable rectal cancer, HDR-EBT is a feasible and safe alternative to EBRT

3. HDR-EBT can be used as a boost technique after EBRT:

-

No increase in toxicity

- No improved outcome (OS, PFS, LC, distant metastases)

- However, higher tumor regression grade potentially interesting for organ

preservation strategies

4. Effective palliation can be obtained with HDR-EBT, which is a simple outpatient

procedure

5. In elderly inoperable patients, trials for EBRT + HDR-EBT as a definitive option are

ongoing