AOAC SPIFAN Stakeholder Panel Meeting Book (March 12, 2020)

Vitamin E SMPR

Standard Method Performance Requirements (SMPR) AOAC SMPR 2011.010: Standard Method Performance Requirements for Vitamin E in Infant Formula and Adult/Pediatric Nutritional Formula a

* Values as mg/100g

Analytical Range

0.2-8*

• Analytical Range • Limit of Detection • Limit of Quantitation • Repeatability • Recovery • Reproducibility

Limit of Detection < 0.1* Limit of Quantitation < 0.2* Repeatability (RSDr) 0.5*

<8%

2.0* 4.0* 8.0*

<6%

mean spiked recovery

Recovery

90-110%

Reproducibility (RSDR) 0.5*

<22% <16%

1.0* 2.0* 3.0* 4.0* 8.0*

Reference Material - NIST 1849 is no longer available Replacement would be NIST 1869

a Concentrations apply to (1) “ready-to-feed” liquids “as is”; (2) reconstituted powders (25 g into 200 mL water); and (3) liquid concentrates diluted 1:1 by weight

* Values as mg/100g

Vitamin E Approved Methods